| Gene Symbol | STUB1 |
| Full Name | STIP1 Homology And U-Box Containing Protein 1 |
| Aliases | CHIP |
| Chromosome | 16p13.3 |
| Protein Family | U-box E3 ubiquitin ligase family |
| Function | encodes a ubiquitin ligase and cochaperone that plays critical roles in protein quality control |
| Molecular Weight | 34.6 kDa |
| Amino Acids | 305 aa |
| Pathways | Chaperone, Proteasome, Ubiquitin-Proteasome |
| UniProt ID | Q9UNE7 |
| NCBI Gene ID | 10273 |
| Ensembl ID | ENSG00000120539 |
| OMIM | 607207 |
| GeneCards | STUB1 |
| Human Protein Atlas | STUB1 |
| Associated Diseases | Als, Amyotrophic Lateral Sclerosis, Ataxia, dementia, frontotemporal, Huntington |
| Known Drugs/Compounds | rapamycin |
| Interactions | amyotrophic lateral sclerosis, AND, AR, ATG, ATG10, ATG12 |
| SciDEX Hypotheses | Kinetic Threshold Model Predicts CHIP-Mediated Cle HSP70 recognition of exposed β-sheet segments trig Exposed amyloidogenic segments trigger CHIP-mediat (+1 more) |
| KG Connections | 245 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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