gene 647 words KG: STIP1
Contents

STIP1 Gene

🧬 Gene Info
Gene SymbolSTIP1
Full NameSTIP1 / HOP
Protein TypeChaperone
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight62.5 kDa
Amino Acids548 aa
PathwaysApoptosis, Chaperone, Tdp-43, autophagy pathway, oxidative stress response
UniProt IDQ9YLS8
GeneCardsSTIP1
Human Protein AtlasSTIP1
Associated DiseasesAls, Amyotrophic Lateral Sclerosis, Ataxia, Huntington, Neuroblastoma, Parkinson
Known Drugs/Compoundsrapamycin
Interactionsamyotrophic lateral sclerosis, AND, APOPTOSIS, AQP4, AQUAPORIN-4, AR
KG Connections193 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (16)

Chaperone-Mediated APOE4 Refolding Enhancement
Score: 0.68
Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.51
CYP46A1 Overexpression Gene Therapy
Score: 0.92
SASP-Driven Aquaporin-4 Dysregulation
Score: 0.78
Aquaporin-4 Polarization Rescue
Score: 0.73

Related Analyses (4)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

Amyotrophic Lateral Sclerosis
redirect · KG edge: associated_with
Apoptosis in Neurodegeneration
entity · KG edge: activates
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
AQP4 (Aquaporin-4 Gene)
gene · KG edge: activates
ar
gene · KG edge: activates

Knowledge Graph (12 edges)

STIP1 associated_with LGALS3
STIP1 associated_with HSPA8
STIP1 associated_with MCOLN1
STIP1 associated_with SQSTM1
STIP1 associated_with SOD1
STIP1 associated_with BCL2
STIP1 associated_with CTSB
STIP1 associated_with TPP1
STIP1 associated_with GLA
STIP1 activates CALCINEURIN

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