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gene 748 words KG: GLA
Contents

GLA Gene - Alpha-Galactosidase A

🧬 Gene Info
Gene SymbolGLA
AliasesPage for GLA Gene
Protein TypeHydrolase
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight50 kDa
Pathwaysautophagy pathway, epigenetic regulation, oxidative stress response
Ensembl IDENSG00000102393
GeneCardsGLA
Human Protein AtlasGLA
Associated DiseasesAls, Amyotrophic Lateral Sclerosis, Ataxia, Cancer, Cardiovascular
Known Drugs/Compoundsrapamycin
InteractionsAR, ATG, ATG10, ATG12, ATP6AP2, CALCINEURIN
KG Connections281 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (11)

Digital Twin-Guided Metabolic Reprogramming
Score: 0.55CYP46A1 Overexpression Gene Therapy
Score: 0.92Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.78Lysosomal Calcium Channel Modulation Therapy
Score: 0.70Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70

Related Analyses (7)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archivedSelective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archivedTDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archivedLipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completedRNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (13)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40Cytochrome Therapeutics
clinical · proposed · Score: 0.40Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40

See Also (10)

Amyotrophic Lateral Sclerosis
redirect · KG edge: associated_withAMPK (AMP-Activated Protein Kinase)
entity · KG edge: associated_withAmyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: associated_withAMBRA1 Gene
gene · KG edge: associated_withar
gene · KG edge: activates

Knowledge Graph (12 edges)

STIP1 associated_with GLA
LGALS3 associated_with GLA
HSPA8 associated_with GLA
MCOLN1 associated_with GLA
SQSTM1 associated_with GLA
SOD1 associated_with GLA
BCL2 associated_with GLA
CTSB associated_with GLA
TPP1 associated_with GLA
GLA activates CALCINEURIN

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