concept

CYP2C19

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CYP2C19: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

50Connections

0Hypotheses

0Analyses

36Outgoing

14Incoming

0Experiments

0Debates

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💡 Concept Info

Name	CYP2C19
Key Genes/Proteins	ABCB1, ABCG2, ACE, ADRA2A, ADRB2, APOE
Related Diseases	Alzheimer's disease
Related Pathways	autophagy pathway

Pathway Diagram

graph TD
    CYP2C19[CYP2C19]
    CYP2C19 -->|modulates| antidepressant_drugs[antidepressant drugs]
    CYP2C19 -->|regulates| CYP2D6[CYP2D6]
    CYP2C19 -->|regulates| CYP3A4[CYP3A4]
    CYP2C19 -->|regulates| PPAR[PPAR]
    CYP2C19 -->|regulates| SLC22A1[SLC22A1]
    CYP2C19 -->|translocates_to| DRD2[DRD2]
    CYP2C19 -->|translocates_to| GCH1[GCH1]
    CYP2C19 -->|translocates_to| GPNMB[GPNMB]
    ABCB1[ABCB1] -->|regulates| CYP2C19
    ACE[ACE] -->|regulates| CYP2C19
    CHAT[CHAT] -->|regulates| CYP2C19
    CHRNA7[CHRNA7] -->|regulates| CYP2C19
    APOE[APOE] -->|translocates_to| CYP2C19
    benchmark_ot_ad_answer_key_CYP[benchmark_ot_ad_answer_key:CYP2C19] -->|data_in| CYP2C19

Outgoing (36)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:CYP2C19	data_in	dataset_row	0.00
antidepressant drugs	modulates	drug	0.85
GSTP1	associated_with	gene	0.60
HMGCR	associated_with	gene	0.60
HTR2C	associated_with	gene	0.60
MAOB	associated_with	gene	0.60
MTHFR	associated_with	gene	0.60
NBEA	associated_with	gene	0.60
OPRM1	associated_with	gene	0.60
SLC30A8	associated_with	gene	0.60
CYP2D6	regulates	gene	0.60
CYP3A4	regulates	gene	0.60
PPAR	regulates	gene	0.60
SLC22A1	regulates	gene	0.60
depression	associated_with	disease	0.60
HTR2A	associated_with	gene	0.60
CYP2E1	associated_with	gene	0.60
CYP3A5	associated_with	gene	0.60
Alzheimer's disease	associated_with	disease	0.60
autophagy pathway	participates_in	pathway	0.60
CYP3A5	regulates	gene	0.60
NR1I2	regulates	gene	0.60
POR	regulates	gene	0.60
CYP2D6	associated_with	gene	0.60
CYP3A4	associated_with	gene	0.60
DRD2	associated_with	gene	0.60
GCH1	associated_with	gene	0.60
GPNMB	associated_with	gene	0.60
LRRK2	associated_with	gene	0.60
NUCKS1	associated_with	gene	0.60
SLC6A2	associated_with	gene	0.60
SLC6A3	associated_with	gene	0.60
SLC6A4	associated_with	gene	0.60
SNCA	associated_with	gene	0.60
GABRA1	associated_with	gene	0.60
PCSK9	associated_with	gene	0.60

Incoming (14)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:CYP2C19	data_in	dataset_row	0.00
ABCG2	associated_with	gene	0.60
ADRA2A	associated_with	gene	0.60
ADRB2	associated_with	gene	0.60
BCHE	associated_with	gene	0.60
CHAT	associated_with	gene	0.60
COMT	associated_with	gene	0.60
ABCB1	regulates	gene	0.60
ACE	regulates	gene	0.60
CHAT	regulates	gene	0.60
CHRNA7	regulates	gene	0.60
ABCB1	associated_with	gene	0.60
APOE	associated_with	gene	0.60
CYP1A2	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CYP2C19 in their description or question text

No additional research found