concept

RETINITIS PIGMENTOSA

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RETINITIS PIGMENTOSA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

69Connections

0Hypotheses

0Analyses

11Outgoing

50Incoming

0Experiments

0Debates

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💡 Concept Info

Name	RETINITIS PIGMENTOSA

Pathway Diagram

graph TD
    RETINITIS_PIGMENTOSA["RETINITIS PIGMENTOSA"]
    style RETINITIS_PIGMENTOSA fill:#1a237e,stroke:#4fc3f7,stroke-width:3px
    RETINITIS_PIGMENTOSA -->|"activates"| Mitochondrial_Function["Mitochondrial Function"]
    RETINITIS_PIGMENTOSA -->|"activates"| Mtor["Mtor"]
    RETINITIS_PIGMENTOSA -->|"activates"| Oxidative_Stress["Oxidative Stress"]
    RETINITIS_PIGMENTOSA -->|"activates"| Glycolysis["Glycolysis"]
    RETINITIS_PIGMENTOSA -->|"activates"| Apoptosis["Apoptosis"]
    RETINITIS_PIGMENTOSA -->|"activates"| Mitophagy["Mitophagy"]
    MYO7A([MYO7A]) -->|"activates"| RETINITIS_PIGMENTOSA
    NRL([NRL]) -->|"activates"| RETINITIS_PIGMENTOSA
    EXOSOMES([EXOSOMES]) -->|"activates"| RETINITIS_PIGMENTOSA
    EGFR([EGFR]) -->|"activates"| RETINITIS_PIGMENTOSA
    MTOR([MTOR]) -->|"activates"| RETINITIS_PIGMENTOSA
    MICROGLIA([MICROGLIA]) -->|"activates"| RETINITIS_PIGMENTOSA
    NEURODEGENERATIVE_DISEASES([NEURODEGENERATIVE DISEASES]) -->|"activates"| RETINITIS_PIGMENTOSA
    GAA([GAA]) -->|"activates"| RETINITIS_PIGMENTOSA
    PARKINSON([PARKINSON]) -->|"activates"| RETINITIS_PIGMENTOSA
    MTDNA([MTDNA]) -->|"activates"| RETINITIS_PIGMENTOSA

Outgoing (11)

Target	Relation	Type	Str
Photoreceptors	causes	cell_type	0.95
aerobic glycolysis	modulates	pathway	0.95
rod photoreceptors	causes	cell_type	0.95
Mtor	activates	pathway	0.55
Apoptosis	associated_with	pathway	0.55
Oxidative Stress	associated_with	pathway	0.55
Oxidative Stress	activates	pathway	0.55
Glycolysis	activates	pathway	0.55
Apoptosis	activates	pathway	0.55
Mitophagy	activates	pathway	0.55
Mitochondrial Function	activates	pathway	0.55

Incoming (58)

Source	Relation	Type	Str
CRB1	associated_with	gene	0.95
TRIM49	risk_factor_for	gene	0.90
USH2A	risk_factor_for	gene	0.85
H105A peptide	treats	compound	0.70
OXIDATIVE STRESS	associated_with	gene	0.65
AGING	associated_with	gene	0.65
PARKINSON	associated_with	gene	0.65
CANCER	associated_with	gene	0.65
ALZHEIMER	associated_with	gene	0.65
ALZHEIMER'S DISEASE	associated_with	gene	0.65
VEGF	associated_with	gene	0.65
AMYOTROPHIC LATERAL SCLEROSIS	associated_with	gene	0.65
PARKINSON'S DISEASE	associated_with	gene	0.65
DIABETIC RETINOPATHY	associated_with	gene	0.65
MYO7A	activates	gene	0.65
NRL	activates	gene	0.65
PARKINSON	activates	gene	0.65
MTDNA	activates	gene	0.65
TFAM	activates	gene	0.65
NRF1	activates	gene	0.65
HUNTINGTON	activates	gene	0.65
DNA	activates	gene	0.65
ATP	activates	gene	0.65
OXIDATIVE STRESS	activates	gene	0.65
AMPK	activates	gene	0.65
PARKIN	activates	gene	0.65
EXERCISE	activates	gene	0.65
ALZHEIMER	activates	gene	0.65
ROS	activates	gene	0.65
SIRT1	activates	gene	0.65
LRRK2	activates	gene	0.65
EPILEPSY	associated_with	gene	0.65
NRF2	activates	gene	0.65
INSULIN RESISTANCE	activates	gene	0.65
DJ-1	activates	gene	0.65
PINK1	activates	gene	0.65
CANCER	activates	gene	0.65
GENES	activates	gene	0.65
MITOCHONDRIAL DYSFUNCTION	activates	gene	0.65
MITOPHAGY	activates	gene	0.65
PPAR	activates	gene	0.65
MITOCHONDRIA	associated_with	gene	0.65
MITOCHONDRIAL DNA	activates	gene	0.65
APOPTOSIS	activates	gene	0.65
GENE MUTATIONS	activates	gene	0.65
EXOSOMES	activates	gene	0.65
EGFR	activates	gene	0.65
MTOR	activates	gene	0.65
APOPTOSIS	associated_with	gene	0.65
MICROGLIA	activates	gene	0.65

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning RETINITIS PIGMENTOSA in their description or question text

No additional research found