Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about AEROBIC GLYCOLYSIS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet.
No AI portrait yet
| Name | AEROBIC GLYCOLYSIS |
graph TD
AEROBIC_GLYCOLYSIS["AEROBIC GLYCOLYSIS"]
AEROBIC_GLYCOLYSIS -->|"regulates"| T_cell_effector_function["T cell effector function"]
AEROBIC_GLYCOLYSIS -->|"component_of"| Warburg_Effect["Warburg Effect"]
AEROBIC_GLYCOLYSIS -->|"contributes to"| Cancer_Metabolism_Reprogrammin["Cancer Metabolism Reprogramming"]
AEROBIC_GLYCOLYSIS -->|"upregulates"| Pyrimidine_Biosynthesis["Pyrimidine Biosynthesis"]
AEROBIC_GLYCOLYSIS -->|"contributes to"| Cognitive_Impairments["Cognitive Impairments"]
Pi3K_Akt_Pathway["Pi3K/Akt Pathway"] -->|"promotes"| AEROBIC_GLYCOLYSIS
HIF_1_["HIF-1alpha"] -->|"upregulates"| AEROBIC_GLYCOLYSIS
IDH2["IDH2"] -->|"upregulates"| AEROBIC_GLYCOLYSIS
HIF1A["HIF1A"] -->|"activates"| AEROBIC_GLYCOLYSIS
HIF1_["HIF1alpha"] -->|"mediates"| AEROBIC_GLYCOLYSIS
MYC["MYC"] -->|"regulates"| AEROBIC_GLYCOLYSIS
HK2["HK2"] -->|"involved_in"| AEROBIC_GLYCOLYSIS| Target | Relation | Type | Str |
|---|---|---|---|
| lactate production | causes | mechanism | 0.90 |
| T cell effector function | regulates | phenotype | 0.90 |
| Warburg Effect | component_of | mechanism | 0.90 |
| Cancer Metabolism Reprogramming | contributes_to | process | 0.90 |
| antitumour immunity | correlates_with | unknown | 0.85 |
| HK2 | activates | protein | 0.85 |
| Pyrimidine Biosynthesis | upregulates | pathway | 0.85 |
| microglial activation | mediates | process | 0.80 |
| Cognitive Impairments | contributes_to | phenotype | 0.80 |
| neuroinflammation | contributes_to | mechanism | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| PI3K | associated_with | entity | 0.95 |
| Retinitis Pigmentosa | modulates | disease | 0.95 |
| PI3K/Akt Pathway | associated_with | pathway | 0.95 |
| AKT1 | associated_with | protein | 0.95 |
| PI3K/AKT | promotes | pathway | 0.95 |
| Bladder Cancer | associated_with | disease | 0.95 |
| Pi3K/Akt Pathway | promotes | pathway | 0.95 |
| HIF1A | associated_with | gene | 0.90 |
| IDH2 | upregulates | gene | 0.90 |
| HIF1A | upregulates | gene | 0.90 |
| AKT1 | promotes | protein | 0.90 |
| HIF-1α | upregulates | protein | 0.90 |
| IDH2 | upregulates | entity | 0.90 |
| HIF1A | activates | entity | 0.90 |
| STING | inhibits | unknown | 0.90 |
| HIF1A | regulates | gene | 0.90 |
| PKM2 | involved_in | gene | 0.90 |
| LDHA | involved_in | gene | 0.90 |
| SRC3 | upregulates | gene | 0.85 |
| HIF1α | mediates | protein | 0.85 |
| GLUT1 | upregulates | gene | 0.85 |
| MYC | regulates | gene | 0.85 |
| PRKAB1 | inhibits | gene | 0.80 |
| PFKFB3 | involved_in | gene | 0.80 |
| PTEN/PI3K/AKT/mTOR | regulates | pathway | 0.80 |
| HK2 | involved_in | gene | 0.80 |
| P53 | regulates | protein | 0.75 |
| AMPK | regulates | protein | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning AEROBIC GLYCOLYSIS in their description or question text
No additional research found