Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MULTIDRUG RESISTANCE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | MULTIDRUG RESISTANCE |
graph TD
MULTIDRUG_RESISTANCE["MULTIDRUG RESISTANCE"]
Als["Als"] -->|"target for"| MULTIDRUG_RESISTANCE
CANCER["CANCER"] -->|"target for"| MULTIDRUG_RESISTANCE
Cancer["Cancer"] -->|"target for"| MULTIDRUG_RESISTANCE
Tumor["Tumor"] -->|"target for"| MULTIDRUG_RESISTANCE
APOPTOSIS["APOPTOSIS"] -->|"regulates"| MULTIDRUG_RESISTANCE
PI3K["PI3K"] -->|"regulates"| MULTIDRUG_RESISTANCE
NF__B["NF-KappaB"] -->|"regulates"| MULTIDRUG_RESISTANCE
AKT["AKT"] -->|"regulates"| MULTIDRUG_RESISTANCE| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| Als | therapeutic_target | disease | 1.00 |
| Cancer | therapeutic_target | disease | 0.90 |
| Tumor | therapeutic_target | disease | 0.90 |
| CANCER | therapeutic_target | gene | 0.90 |
| Cancer | regulates | disease | 0.70 |
| Als | activates | disease | 0.70 |
| PI3K | regulates | gene | 0.70 |
| NF-ΚB | regulates | gene | 0.70 |
| CANCER | regulates | gene | 0.70 |
| AKT | regulates | gene | 0.70 |
| Carcinoma | therapeutic_target | disease | 0.70 |
| APOPTOSIS | regulates | gene | 0.70 |
| NF-ΚB | therapeutic_target | gene | 0.70 |
| Leukemia | therapeutic_target | disease | 0.70 |
| MYC | therapeutic_target | gene | 0.70 |
| AKT | therapeutic_target | gene | 0.70 |
| Cancer | activates | disease | 0.70 |
| GENES | activates | gene | 0.70 |
| CANCER | activates | gene | 0.70 |
| ABCB1 | activates | gene | 0.60 |
| BCL2 | therapeutic_target | gene | 0.60 |
| ATP | activates | gene | 0.60 |
| CD44 | therapeutic_target | gene | 0.60 |
| YBX1 | activates | gene | 0.60 |
| EGFR | activates | gene | 0.60 |
| ERBB2 | activates | gene | 0.60 |
| CYTOKINES | therapeutic_target | gene | 0.60 |
| ABCB1 | therapeutic_target | gene | 0.60 |
| CANCER | inhibits | gene | 0.60 |
| MICROTUBULES | therapeutic_target | gene | 0.60 |
| Cancer | inhibits | disease | 0.60 |
| TFEB | activates | gene | 0.60 |
| LYSOSOMAL BIOGENESIS | activates | gene | 0.60 |
| ROS | activates | gene | 0.60 |
| LYSOSOME | activates | gene | 0.60 |
| ATP1B1 | activates | gene | 0.60 |
| AUTOPHAGY | activates | gene | 0.60 |
| Tumor | activates | disease | 0.60 |
| AUTOPHAGY | therapeutic_target | gene | 0.60 |
| Breast Cancer | activates | disease | 0.60 |
| NEURODEGENERATION | therapeutic_target | gene | 0.60 |
| Neurodegeneration | therapeutic_target | disease | 0.60 |
| REST | therapeutic_target | gene | 0.60 |
| APOPTOSIS | therapeutic_target | gene | 0.60 |
| Cardiovascular | therapeutic_target | disease | 0.60 |
| GENES | regulates | gene | 0.60 |
| ASTROCYTE | therapeutic_target | gene | 0.60 |
| OVERVIEW | therapeutic_target | gene | 0.60 |
| SND1 | therapeutic_target | gene | 0.60 |
| Glioma | therapeutic_target | disease | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning MULTIDRUG RESISTANCE in their description or question text
No additional research found