gene

SND1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SND1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

28Connections

0Hypotheses

0Analyses

14Outgoing

14Incoming

0Experiments

0Debates

Summary

SND1 is a gene implicated in neurodegeneration research. Key relationships include: therapeutic target, interacts with, implicated in. Associated with Als, Cancer, Glioma. Connected to 29 entities in the SciDEX knowledge graph.

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🧬 Gene Info

Gene Symbol	SND1
Full Name	Stonin 1
Chromosome	1p36.22
Protein Type	Adaptor Protein
Function	encodes a specialized adaptor protein that plays a critical role in synaptic vesicle endocytosis.
Primary Expression	neurons throughout the central nervous system, with particularly high levels in the hippocampus, cerebral cortex, and cerebellum
Molecular Weight	85 kDa
Amino Acids	758 aa
Exons	27
UniProt ID	[Q9Y285](https://www.uniprot.org/uniprotkb/Q9Y285)
Ensembl ID	ENSG00000163511
OMIM	607417
GeneCards	SND1
Human Protein Atlas	SND1
Associated Diseases	neurodegeneration
Interactions	CANCER, FMR1, G3BP1, NONO, NPM1, SQSTM1
KG Connections	28 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SND1 — Stonin 1

gene · 2073 words

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Pathway Diagram

graph TD
    SND1["SND1"]
    Ms{"Ms"}
    SND1 -->|"interacts with"| Ms
    Cancer{"Cancer"}
    SND1 -->|"interacts with"| Cancer
    neurodegeneration["neurodegeneration"]
    SND1 -->|"implicated in"| neurodegeneration
    NPM1["NPM1"]
    NPM1 -->|"interacts with"| SND1
    G3BP1["G3BP1"]
    G3BP1 -->|"interacts with"| SND1
    NONO["NONO"]
    NONO -->|"interacts with"| SND1
    CANCER["CANCER"]
    CANCER -->|"interacts with"| SND1
    SQSTM1["SQSTM1"]
    SQSTM1 -->|"interacts with"| SND1
    FMR1["FMR1"]
    FMR1 -->|"interacts with"| SND1
    style SND1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (14)

Target	Relation	Type	Str
Ms	interacts_with	disease	0.65
Cancer	interacts_with	disease	0.65
Tumor	therapeutic_target	disease	0.65
Glioma	therapeutic_target	disease	0.65
Cancer	therapeutic_target	disease	0.65
Als	therapeutic_target	disease	0.65
Pi3K/Akt	therapeutic_target	pathway	0.60
Drug Resistance	therapeutic_target	pathway	0.60
Epithelial-Mesenchymal Transition	therapeutic_target	pathway	0.60
Apoptosis	therapeutic_target	pathway	0.60
Wnt	therapeutic_target	pathway	0.60
Metastasis	therapeutic_target	pathway	0.60
Nf-Κb	therapeutic_target	pathway	0.60
Multidrug Resistance	therapeutic_target	pathway	0.60

Incoming (14)

Source	Relation	Type	Str
CANCER	interacts_with	gene	0.60
APOPTOSIS	therapeutic_target	gene	0.60
NF-ΚB	therapeutic_target	gene	0.60
CANCER	therapeutic_target	gene	0.60
GENES	therapeutic_target	gene	0.60
ASTROCYTE	therapeutic_target	gene	0.60
NPM1	interacts_with	gene	0.60
G3BP1	interacts_with	gene	0.60
NONO	interacts_with	gene	0.60
SQSTM1	interacts_with	gene	0.60
FMR1	interacts_with	gene	0.60
PI3K	therapeutic_target	gene	0.60
AKT	therapeutic_target	gene	0.60
OVERVIEW	therapeutic_target	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SND1 in their description or question text

No additional research found