concept

MIR454

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MIR454: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

92Connections

0Hypotheses

0Analyses

47Outgoing

45Incoming

0Experiments

0Debates

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💡 Concept Info

Name	MIR454
Key Genes/Proteins	Actin, AMPK, AND, APC, ATG, AUTOPHAGY
Related Diseases	Als, ALS, cancer, Cancer
Related Pathways	Autophagy, autophagy pathway

Pathway Diagram

graph TD
    MIR454["MIR454"]
    MIR454 -->|"regulates"| FAM83A["FAM83A"]
    MIR454 -->|"regulates"| TSPAN1["TSPAN1"]
    MIR454 -->|"activates"| Tumor["Tumor"]
    MIR454 -->|"activates"| Cancer["Cancer"]
    MIR454 -->|"activates"| ALS["ALS"]
    MIR454 -->|"activates"| Als["Als"]
    MIR454 -->|"activates"| Autophagy["Autophagy"]
    MIR454 -->|"activates"| Wnt["Wnt"]
    WNT["WNT"] -->|"activates"| MIR454
    CTNNB1["CTNNB1"] -->|"activates"| MIR454
    AUTOPHAGY["AUTOPHAGY"] -->|"activates"| MIR454
    FAM83A -->|"activates"| MIR454
    AND["AND"] -->|"activates"| MIR454
    P62["P62"] -->|"activates"| MIR454
    CANCER["CANCER"] -->|"activates"| MIR454
    TSPAN1 -->|"activates"| MIR454

Outgoing (47)

Target	Relation	Type	Str
FAM83A	regulates	gene	0.85
TSPAN1	regulates	gene	0.85
Als	activates	disease	0.65
Carcinoma	associated_with	disease	0.65
Tumor	activates	disease	0.65
Cancer	activates	disease	0.65
ALS	activates	disease	0.65
Mtor	associated_with	pathway	0.60
Autophagy	activates	pathway	0.60
Wnt	activates	pathway	0.60
MAP1LC3	associated_with	gene	0.60
Actin	associated_with	protein	0.60
ATG	associated_with	gene	0.60
AMPK	associated_with	gene	0.60
MTOR	associated_with	gene	0.60
GAPDH	associated_with	gene	0.60
CCND1	associated_with	gene	0.60
AXIN2	associated_with	gene	0.60
FAM83A	activates	gene	0.60
RAB7A	associated_with	gene	0.60
GFP	associated_with	gene	0.60
Raf	activates	protein	0.60
AUTOPHAGY	activates	gene	0.60
TCF4	associated_with	gene	0.60
GSK3B	associated_with	gene	0.60
BECN1	associated_with	gene	0.60
RAS	associated_with	gene	0.60
AXIN	associated_with	gene	0.60
TSPAN1	activates	gene	0.60
LAMP1	associated_with	gene	0.60
LC3	associated_with	gene	0.60
MYC	associated_with	gene	0.60
WNT	activates	gene	0.60
autophagy pathway	participates_in	pathway	0.60
TSPAN1	targets	gene	0.60
TSPAN1	associated_with	gene	0.60
MTOR	activates	gene	0.60
MYC	activates	gene	0.60
RAB7A	activates	gene	0.60
RAS	activates	gene	0.60
RNA	activates	gene	0.60
SQSTM1	activates	gene	0.60
TCF4	activates	gene	0.60
Wnt signaling	participates_in	pathway	0.60
cancer	activates	disease	0.60
cancer	associated_with	disease	0.60
MKI67	activates	gene	0.60

Incoming (45)

Source	Relation	Type	Str
FAM83A	targets	gene	0.60
FAM83A	associated_with	gene	0.60
AMPK	activates	gene	0.60
APC	activates	gene	0.60
ATG	activates	gene	0.60
AXIN2	activates	gene	0.60
BECN1	activates	gene	0.60
CCND1	activates	gene	0.60
CSNK1A1	activates	gene	0.60
GAPDH	activates	gene	0.60
GFP	activates	gene	0.60
GSK3B	activates	gene	0.60
LAMP1	activates	gene	0.60
LC3	activates	gene	0.60
MAP1LC3	activates	gene	0.60
rapamycin	targets	drug	0.60
LAMP1	associated_with	gene	0.60
LC3	associated_with	gene	0.60
RAB7A	associated_with	gene	0.60
WNT	activates	gene	0.60
RAS	associated_with	gene	0.60
GSK3B	associated_with	gene	0.60
APC	associated_with	gene	0.60
CSNK1A1	associated_with	gene	0.60
SQSTM1	associated_with	gene	0.60
GFP	associated_with	gene	0.60
GAPDH	associated_with	gene	0.60
AXIN2	associated_with	gene	0.60
RNA	associated_with	gene	0.60
CYCLIN D1	associated_with	gene	0.60
BECN1	associated_with	gene	0.60
CTNNB1	activates	gene	0.60
AUTOPHAGY	activates	gene	0.60
AMPK	associated_with	gene	0.60
FAM83A	activates	gene	0.60
AND	activates	gene	0.60
P62	activates	gene	0.60
CANCER	activates	gene	0.60
CCND1	associated_with	gene	0.60
MYC	associated_with	gene	0.60
ATG	associated_with	gene	0.60
TCF4	associated_with	gene	0.60
TSPAN1	activates	gene	0.60
AXIN	associated_with	gene	0.60
MTOR	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MIR454 in their description or question text

No additional research found