concept

KINESIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KINESIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

65Connections

1Hypotheses

0Analyses

11Outgoing

50Incoming

0Experiments

0Debates

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💡 Concept Info

Name	KINESIN

Pathway Diagram

graph TD
    KINESIN["KINESIN"]
    KINESIN -->|"interacts"| Alzheimer["Alzheimer"]
    KINESIN -->|"interacts"| Als["Als"]
    KINESIN -->|"expressed in"| Neurodegeneration["Neurodegeneration"]
    KINESIN -->|"interacts"| Cholesterol["Cholesterol"]
    KINESIN -->|"interacts"| Apoptosis["Apoptosis"]
    KINESIN -->|"transports"| Oxidative_Phosphorylation["Oxidative Phosphorylation"]
    KINESIN -->|"expressed in"| Oxidative_Stress["Oxidative Stress"]
    ATP["ATP"] -->|"binds"| KINESIN
    IL6["IL6"] -->|"interacts"| KINESIN
    PARP1["PARP1"] -->|"interacts"| KINESIN
    SREBF1["SREBF1"] -->|"interacts"| KINESIN
    IL1B["IL1B"] -->|"interacts"| KINESIN
    PSEN1["PSEN1"] -->|"interacts"| KINESIN
    EIF2AK2["EIF2AK2"] -->|"interacts"| KINESIN
    APH1B["APH1B"] -->|"interacts"| KINESIN

Outgoing (11)

Target	Relation	Type	Str
Neurodegeneration	expressed_in	disease	0.60
Alzheimer	expressed_in	disease	0.60
Alzheimer	interacts_with	disease	0.60
Als	interacts_with	disease	0.60
Cholesterol	interacts_with	pathway	0.55
Apoptosis	interacts_with	pathway	0.55
Apoptosis	associated_with	pathway	0.55
Cell Cycle	associated_with	pathway	0.55
Neurogenesis	associated_with	pathway	0.55
Oxidative Phosphorylation	transports	pathway	0.55
Oxidative Stress	expressed_in	pathway	0.55

Incoming (54)

Source	Relation	Type	Str
ATP	binds	entity	0.70
8205624	is described as	paper	0.60
BORC	associated_with	gene	0.60
RNA	associated_with	gene	0.60
AXON	associated_with	gene	0.60
APOPTOSIS	associated_with	gene	0.60
TRAK1	regulates	gene	0.60
MITOCHONDRIA	contributes_to	gene	0.60
NEURON	transports	gene	0.60
TRAK1	expressed_in	gene	0.60
AXON	interacts_with	gene	0.60
MITOCHONDRIA	transports	gene	0.60
IL6	interacts_with	gene	0.60
PARP1	interacts_with	gene	0.60
SREBF1	interacts_with	gene	0.60
IL1B	interacts_with	gene	0.60
PSEN1	interacts_with	gene	0.60
EIF2AK2	interacts_with	gene	0.60
APH1B	interacts_with	gene	0.60
HSPG2	interacts_with	gene	0.60
A2M	interacts_with	gene	0.60
HMGCR	interacts_with	gene	0.60
DYNEIN	associated_with	gene	0.60
NCSTN	interacts_with	gene	0.60
KIF5A	interacts_with	gene	0.60
KIF5A	associated_with	gene	0.60
KIF5C	associated_with	gene	0.60
TAU	activates	gene	0.60
DYNEIN	activates	gene	0.60
OPA1	expressed_in	gene	0.60
MIRO1	regulates	gene	0.60
KIF23	associated_with	gene	0.60
DAPK1	interacts_with	gene	0.60
APP	interacts_with	gene	0.60
PSEN2	interacts_with	gene	0.60
MAPT	associated_with	gene	0.60
TNF	interacts_with	gene	0.60
LMNA	interacts_with	gene	0.60
PEN2	interacts_with	gene	0.60
APOE	interacts_with	gene	0.60
FAS	interacts_with	gene	0.60
DHCR24	interacts_with	gene	0.60
MIRO1	transports	gene	0.60
ALZHEIMER	interacts_with	gene	0.60
DNA	interacts_with	gene	0.60
AMYLOID	interacts_with	gene	0.60
APOPTOSIS	interacts_with	gene	0.60
TFCP2	interacts_with	gene	0.60
TRAK1	interacts_with	gene	0.60
ALZHEIMER	expressed_in	gene	0.60

Targeting Hypotheses (1)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
Kinesin-Dependent Peripheral Microtubule Transport Maintains	0.486	neurodegeneration	What determines the spatial organization

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning KINESIN in their description or question text

No additional research found