Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ABP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | ABP |
| Key Genes/Proteins | ATG16L1, BCL2, CALCOCO2, CASP3, DMSO, GAPDH |
| Related Pathways | apoptosis pathway, autophagy pathway, mitochondrial function |
| Linked Hypotheses | 1 hypotheses |
Knowledge base pages for this entity
graph TD
ABP[ABP]
ABP -->|regulates| SGMS1[SGMS1]
ABP -->|activates| ATG16L1[ATG16L1]
ABP -->|activates| LC3[LC3]
ABP -->|activates| BCL2[BCL2]
ABP -->|activates| CALCOCO2[CALCOCO2]
ABP -->|activates| CASP3[CASP3]
ABP -->|activates| GAPDH[GAPDH]
ABP -->|activates| HTT[HTT]
ABP -->|activates| MFF[MFF]
ABP -->|activates| NBR1[NBR1]
benchmark_ot_ad_answer_key_ABP[benchmark_ot_ad_answer_key:ABP] -->|data_in| ABP| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:ABP | data_in | dataset_row | 0.00 |
| autophagy pathway | participates_in | pathway | 0.60 |
| apoptosis pathway | participates_in | pathway | 0.60 |
| mitochondrial function | participates_in | pathway | 0.60 |
| DMSO | activates | gene | 0.60 |
| GFP | activates | gene | 0.60 |
| MAP1LC3 | activates | gene | 0.60 |
| NLR | activates | gene | 0.60 |
| ubiquitin-proteasome | participates_in | pathway | 0.60 |
| SGMS1 | regulates | gene | 0.60 |
| ATG16L1 | activates | gene | 0.60 |
| LC3 | activates | gene | 0.60 |
| BCL2 | activates | gene | 0.60 |
| CALCOCO2 | activates | gene | 0.60 |
| CASP3 | activates | gene | 0.60 |
| GAPDH | activates | gene | 0.60 |
| HTT | activates | gene | 0.60 |
| MFF | activates | gene | 0.60 |
| NBR1 | activates | gene | 0.60 |
| NDP52 | activates | gene | 0.60 |
| NLRX1 | activates | gene | 0.60 |
| OPTN | activates | gene | 0.60 |
| PINK1 | activates | gene | 0.60 |
| PRKN | activates | gene | 0.60 |
| PTEN | activates | gene | 0.60 |
| TIMM23 | activates | gene | 0.60 |
| TMEM59 | activates | gene | 0.60 |
| Parkinson's disease | activates | disease | 0.60 |
| TOMM20 | activates | gene | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:ABP | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| FABP5/7 Inhibition (H2): Lipid Relay Interruption | 0.670 | neurodegeneration | Does restoring neuronal AMPK activity re |
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ABP in their description or question text
No additional research found