gene 1,270 words KG: HSPB8
Contents

HSPB8 Gene

🧬 Gene Info
Gene SymbolHSPB8
Full NameHeat Shock Protein Family B Member 8
Chromosome21q22.3
Protein FamilySmall heat shock protein (sHsp)
Molecular Weight22 kDa
Amino Acids196 aa
PathwaysAutophagy
UniProt IDQ9UJX1
NCBI Gene ID23673
Ensembl IDENSG00000169435
OMIM607655
GeneCardsHSPB8
Human Protein AtlasHSPB8
Associated DiseasesAls, Amyotrophic Lateral Sclerosis, Ataxia, Huntington, Neuroblastoma
Known Drugs/Compoundsrapamycin
Interactionsamyotrophic lateral sclerosis, AND, AR, ATG, ATG10, ATG12
KG Connections216 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (8)

HSP70 Co-chaperone DNAJB6 Universal Cross-Seeding Inhibitor
Score: 0.54
Lysosomal Calcium Channel Modulation Therapy
Score: 0.70
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
Cross-Seeding Prevention Strategy
Score: 0.69
Lysosomal Positioning Dynamics Modulation
Score: 0.69

Related Analyses (3)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (2)

Gene expression analysis of autophagy targets following treh
exploratory · proposed · Score: 0.85
Trehalose-induced autophagy gene expression analysis
exploratory · proposed · Score: 0.85

See Also (8)

Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
ar
gene · KG edge: activates
ATG10 Gene
gene · KG edge: activates
ATG12 — Autophagy Related 12
gene · KG edge: activates
BAG3 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

STIP1 associated_with HSPB8
LGALS3 associated_with HSPB8
HSPA8 associated_with HSPB8
MCOLN1 associated_with HSPB8
SQSTM1 associated_with HSPB8
SOD1 associated_with HSPB8
BCL2 associated_with HSPB8
CTSB associated_with HSPB8
TPP1 associated_with HSPB8
GLA associated_with HSPB8

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