protein 636 words KG: TIMM22
Contents

TIMM22 Protein

🔬 Protein Info
Gene SymbolTIMM22
Chromosome17p13.2
Protein FamilyTranslocase of inner mitochondrial membrane (TIM) family
Functionis an essential component of the TIM22 complex, which mediates the insertion of carrier proteins into the mitochondrial inner membrane.
Primary ExpressionMitochondrial inner membrane
Subcellular LocalizationMitochondrial inner membrane
Molecular Weight25 kDa
Amino Acids227 aa
UniProt IDQ9Y5J7
GeneCardsTIMM22
Human Protein AtlasTIMM22
Associated DiseasesParkinson's Disease, Mitochondrial Disorders
InteractionsBECN1, BNIP3, BNIP3L, CEBPB, DDIT3, DNM1L
KG Connections43 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

UniProtWikipedia

Related Hypotheses (5)

TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (7)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (15)

SPG7 (Redirect)
redirect · KG edge: inhibits
mTOR Signaling Dysregulation in Progressive Supranuclea
event · KG edge: inhibits
BECN1 Gene
gene · KG edge: inhibits
BNIP3 Gene
gene · KG edge: inhibits
BNIP3L — BCL2 Interacting Protein 3 Like (NIX)
gene · KG edge: inhibits

Knowledge Graph (12 edges)

BNIP3 inhibits TIMM22
VDAC1 inhibits TIMM22
FUNDC1 inhibits TIMM22
TOMM20 inhibits TIMM22
TIMM9 inhibits TIMM22
TIMM17B inhibits TIMM22
OMA1 inhibits TIMM22
TIMM23 inhibits TIMM22
MTOR inhibits TIMM22
NRF1 inhibits TIMM22

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