gene 1,654 words KG: TOMM20
Contents

TOMM20 — Translocase of Outer Mitochondrial Membrane 20

🧬 Gene Info
Gene SymbolTOMM20
Full NameTranslocase of Outer Mitochondrial Membrane 20
Chromosome5q33.1
Protein TypeGene
Functionis a gene located on chromosome 5q33.
Molecular Weight18 kDa
Amino Acids169 aa
PathwaysMitophagy
NCBI Gene ID98004
Ensembl IDENSG00000160948
GeneCardsTOMM20
Human Protein AtlasTOMM20
Associated DiseasesAging, Alzheimer, Cardiovascular, Ischemia, Melanoma, Parkinson
Known Drugs/CompoundsSpautin-1
InteractionsABP, ACTB, AGING, AIFM1, ALZHEIMER, ALZHEIMER DISEASE
KG Connections389 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

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Knowledge Graph

Related Hypotheses (19)

Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.91
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.81
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73

Related Analyses (12)

Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (15)

AMPK (AMP-Activated Protein Kinase)
entity · KG edge: interacts_with
Apoptosis in Neurodegeneration
entity · KG edge: associated_with
ACTB Gene
gene · KG edge: activates
AMBRA1 Gene
gene · KG edge: activates
ANG — Angiogenin
gene · KG edge: treats

Knowledge Graph (12 edges)

DRP1 regulates TOMM20
TOMM20 regulates MAX
TOMM20 regulates MIRO1
TOMM20 regulates MID51
TOMM20 regulates MID49
TOMM20 regulates MFF
PARKIN associated_with TOMM20
BCL2L13 associated_with TOMM20
TOMM20 associated_with ATG7
TOMM20 associated_with GAPDH

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