gene 538 words KG: EIF2A
Contents

EIF2A Gene

🧬 Gene Info
Gene SymbolEIF2A
Full NameEukaryotic Translation Initiation Factor 2A
Chromosome3q27.1
FunctionBinds the 40S ribosomal subunit
PathwaysAkt, Apoptosis, Er Stress, Wnt
UniProt IDQ9Y5Q3
NCBI Gene ID27185
Ensembl IDENSG00000144895
OMIM609994
GeneCardsEIF2A
Human Protein AtlasEIF2A
Associated Diseasesneurodegeneration
Known Drugs/Compoundsrapamycin
InteractionsActin, AKT, AKT1, AKT1S1, ALS, ALZHEIMER
KG Connections533 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (7)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.91
Phase-Separated Organelle Targeting
Score: 0.73
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72

Related Analyses (5)

Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (11)

AMPK (AMP-Activated Protein Kinase)
entity · KG edge: interacts_with
Apoptosis in Neurodegeneration
entity · KG edge: activates
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: inhibits
AKT1 Gene
gene · KG edge: interacts_with
AMBRA1 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

OPTN interacts_with EIF2A
CASP3 interacts_with EIF2A
AKT1 interacts_with EIF2A
CALCOCO2 interacts_with EIF2A
CGAS interacts_with EIF2A
CFTR interacts_with EIF2A
SQSTM1 interacts_with EIF2A
RPS6KB1 interacts_with EIF2A
GRB2 interacts_with EIF2A
RHEB interacts_with EIF2A

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