| Gene Symbol | IRE1 |
| Function | Inositol-requiring enzyme 1 (IRE1) is the most evolutionarily conserved sensor of the unfolded protein response (UPR) |
| Molecular Weight | 110 kDa |
| Pathways | Endoplasmic Reticulum Stress |
| GeneCards | IRE1 |
| Human Protein Atlas | IRE1 |
| Associated Diseases | Cardiovascular, Diabetes, Neurodegeneration |
| Known Drugs/Compounds | Dolutegravir, DTG, rapamycin |
| Interactions | AND, APOPTOSIS, ATF4, ATF6, ATG, AUTOPHAGY |
| KG Connections | 224 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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