| Gene Symbol | CXCL2 |
| Full Name | C-X-C Motif Chemokine Ligand 2 |
| Aliases | MIP-2 |
| Chromosome | 4q21.1 |
| Function | is a small chemokine protein that plays critical roles in inflammation, immune cell recruitment, and neuroinflammation. |
| Molecular Weight | 7.8 kDa |
| Amino Acids | 99 aa |
| Pathways | PI3K, MAPK, NF-κB pathway |
| UniProt ID | [P19875](https://www.uniprot.org/uniprot/P19875) |
| Ensembl ID | ENSG00000024836 |
| GeneCards | CXCL2 |
| Human Protein Atlas | CXCL2 |
| N-terminal region | Contains the ELR motif (Glu-Leu-Arg) essential for receptor binding and angiogenic activity |
| CXC motif | Conserved cysteine-cysteine arrangement |
| C-terminal heparin-binding domain | Mediates interaction with extracellular matrix |
| Associated Diseases | Alzheimer, Inflammation |
| Interactions | AGING, Akt, ALZHEIMER, ALZHEIMER'S DISEASE, AND, APOPTOSIS |
| KG Connections | 265 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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