gene 670 words KG: ABCD3
Contents

ABCD3 Gene

🧬 Gene Info
Gene SymbolABCD3
Chromosome1p22.1
Protein FamilyABC transporter subfamily D
Protein TypeTransporter
FunctionABCD3 functions as a peroxisomal membrane transporter
Primary Expressionmultiple tissues, with highest levels in liver, kidney, and brain
Subcellular LocalizationPeroxisomal membrane
Molecular Weight79.7 kDa
PathwaysTgf-Beta, Wnt
UniProt ID[O75323](https://www.uniprot.org/uniprot/O75323)
GeneCardsABCD3
Human Protein AtlasABCD3
Associated DiseasesAD, ALI, Als, Alzheimer, Cancer
InteractionsABCD1, ABCD2, Actin, ALS, ALZHEIMER, ALZHEIMER DISEASE
KG Connections475 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (9)

Liquid-Liquid Phase Separation Modifier Therapy
Score: 0.55
CYP46A1 Overexpression Gene Therapy
Score: 0.92
Phase-Separated Organelle Targeting
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72
Mitochondrial Transfer Pathway Enhancement
Score: 0.70

Related Analyses (4)

Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (9)

ABCA2 Gene - ATP Binding Cassette Subfamily A Member 2
gene · KG edge: expressed_in
ABCD1 — ATP Binding Cassette Subfamily D Member 1
gene · KG edge: activates
ABCD2 — ATP Binding Cassette Subfamily D Member 2
gene · KG edge: activates
ABCG1 Gene
gene · KG edge: expressed_in
ABCG2 (BCRP) - ATP Binding Cassette Subfamily G Member
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

CAT interacts_with ABCD3
OPTN interacts_with ABCD3
DNM1L interacts_with ABCD3
CANX interacts_with ABCD3
LGALS3 interacts_with ABCD3
CALCOCO2 interacts_with ABCD3
G3BP1 interacts_with ABCD3
PEX3 interacts_with ABCD3
SQSTM1 interacts_with ABCD3
BCL2 interacts_with ABCD3

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