| Gene Symbol | HSPA5 / GRP78 / BiP |
| Full Name | Heat Shock Protein Family A (Hsp70) Member 5 |
| Aliases | Hsp70 |
| Chromosome | 9q33.3 |
| Protein Family | Hsp70 family (ER-resident) |
| Protein Type | Chaperone |
| Function | HSPA5/GRP78 is a BiP (Binding Immunoglobulin Protein) that resides in the ER lumen. |
| Primary Expression | brain, particularly in neurons and glia |
| Pathways | Akt, Autophagy, Lipid Metabolism, Wnt |
| UniProt ID | P11021 |
| NCBI Gene ID | 3309 |
| Ensembl ID | ENSG00000156006 |
| OMIM | 138120 |
| Location | Chromosome 9q33.3 |
| Protein | HSPA5/GRP78/BiP |
| Associated Diseases | Aging, Atherosclerosis, Diabetes |
| Known Drugs/Compounds | rapamycin |
| Interactions | ACETYL-COA, AKT, AKT1, AKT1S1, AMBRA1, AMPK |
| KG Connections | 488 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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