gene 640 words KG: BCL2L13
Contents

BCL2L13

🧬 Gene Info
Gene SymbolBCL2L13
Full NameBCL2 Like 13
Chromosome22q11.21
Protein TypeMitochondrial Outer Membrane Protein
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight32 kDa
PathwaysApoptosis, Er Stress, Immune Response, MAPK signaling, Mitochondrial Function
UniProt ID[Q9HAW5](https://www.uniprot.org/uniprot/Q9HAW5)
GeneCardsBCL2L13
Human Protein AtlasBCL2L13
Associated DiseasesAD, Aging, ALI, Als, Alzheimer
InteractionsABCD3, Actin, AGING, ALS, ALZHEIMER, ALZHEIMER DISEASE
KG Connections717 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (11)

Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.79
Liquid-Liquid Phase Separation Modifier Therapy
Score: 0.55
APOE-Dependent Autophagy Restoration
Score: 0.88
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
Phase-Separated Organelle Targeting
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72
Autophagosome Maturation Checkpoint Control
Score: 0.71
Mitochondrial Transfer Pathway Enhancement
Score: 0.70
RNA Granule Nucleation Site Modulation
Score: 0.66
Sphingolipid Metabolism Reprogramming
Score: 0.62
Prohibitin-2 Mitochondrial Cross-Seeding Hub Disruption
Score: 0.47

Related Analyses (4)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (3)

Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.40
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.40
Mixed Pathology Effects on Parkinson's Disease Progression a
clinical · proposed · Score: 0.40

See Also (10)

AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: activates
ABCD3 Gene
gene · KG edge: interacts_with
AMBRA1 Gene
gene · KG edge: interacts_with
Alzheimer Indonesia
institution · KG edge: interacts_with

Knowledge Graph (12 edges)

CAT interacts_with BCL2L13
OPTN interacts_with BCL2L13
DNM1L interacts_with BCL2L13
CANX interacts_with BCL2L13
LGALS3 interacts_with BCL2L13
CALCOCO2 interacts_with BCL2L13
G3BP1 interacts_with BCL2L13
PEX3 interacts_with BCL2L13
SQSTM1 interacts_with BCL2L13
LMNA interacts_with BCL2L13

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