Contents

PPP1R15A Gene

🧬 Gene Info

Gene Symbol	PPP1R15A
Aliases	GADD34
Chromosome	19q13
Protein Type	Gene
Function	encodes a stress-inducible scaffold that recruits catalytic PP1 phosphatase to phospho-eIF2alpha substrates.
Pathways	Blood-Brain Barrier, Er Stress
GeneCards	PPP1R15A
Human Protein Atlas	PPP1R15A
Neurons	PPP1R15A may influence synaptic maintenance versus stress-induced dendritic simplification via translational control.[@scheper2015][@halliday2015]
Associated Diseases	neurodegeneration
Interactions	AND, ATF4, CLDN5, CXCL1, CXCL2, CYTOKINES
KG Connections	64 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

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