gene 759 words KG: MYC
Contents

MYC Gene

🧬 Gene Info
Gene SymbolMYC
Chromosome8q24.21
Functionis an important component in the neurobiology of neurodegenerative diseases.
Exons3
PathwaysAkt, Amyloid, Angiogenesis, Apoptosis, Autophagy
Ensembl IDENSG00000136997
GeneCardsMYC
Human Protein AtlasMYC
Associated DiseasesAging, Als, Alzheimer, Alzheimer's disease, Amyotrophic Lateral Sclerosis
Known Drugs/CompoundsBazhen Decoction, COENZYME Q10, LWDHD, MYC inhibitors, rapamycin, RAPAMYCIN
Interactions66CTG peptide, ABCD1, ABCD2, ABL1, ACETYL-COA, ACHE
KG Connections2154 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (30)

ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro
Score: 0.85
Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.56
CYP46A1 Overexpression Gene Therapy
Score: 0.92
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.91
Transcriptional Autophagy-Lysosome Coupling
Score: 0.88

Related Analyses (5)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (2)

PDGFRA and C-MYC protein validation in ovarian cancer tissue
exploratory · proposed · Score: 0.85
Neural Stem Cell Therapy for Alzheimer's Disease
clinical · proposed · Score: 0.40

See Also (11)

ABCB1 (MDR1) - ATP Binding Cassette Subfamily B Member
gene · KG edge: therapeutic_target
ABCD1 — ATP Binding Cassette Subfamily D Member 1
gene · KG edge: activates
ABCD2 — ATP Binding Cassette Subfamily D Member 2
gene · KG edge: activates
ACSL4 Gene - Acyl-CoA Synthetase Long Chain Family Memb
gene · KG edge: regulates
ACTB Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

STAT3 regulates MYC
ACTB regulates MYC
PPARA regulates MYC
CAT regulates MYC
SQSTM1 regulates MYC
RPS6KB1 regulates MYC
RAB7A regulates MYC
SREBF1 regulates MYC
EIF4EBP1 regulates MYC
CTSD regulates MYC

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