gene 1,725 words KG: ACTB
Contents

ACTB Gene

🧬 Gene Info
Gene SymbolACTB
Full NameBeta-Actin
Chromosome7p22.1
Functionis a globular protein with a molecular weight of approximately 42 kDa.
Molecular Weight42 kDa
Exons6
PathwaysAutophagy, Chaperone, Mapk, Mtor, Oxidative Stress
UniProt IDP60709
NCBI Gene ID81
Ensembl IDENSG00000075624
OMIM102630
GeneCardsACTB
Human Protein AtlasACTB
Associated DiseasesAD, ADH, ALI, Als, Alzheimer, AMI
Known Drugs/Compoundsrapamycin, statins
Interactions4E-BP1, ABCA1, ABCG1, ACTG1, Actin, AGING
KG Connections1093 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (30)

Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.91
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Autophagosome Maturation Checkpoint Control
Score: 0.71
Lysosomal Calcium Channel Modulation Therapy
Score: 0.70
Blood-Brain Barrier SPM Shuttle System
Score: 0.53

Related Analyses (9)

Gene expression changes in aging mouse brain predicting neur
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (8)

ABCA1 - ATP-Binding Cassette Transporter A1
gene · KG edge: activates
ABCG1 Gene
gene · KG edge: interacts_with
ACTG1 Gene
gene · KG edge: associated_with
AIF1 Gene
gene · KG edge: associated_with
AKT1 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

ACTB regulates PPARA
ACTB regulates CAT
ACTB regulates SQSTM1
ACTB regulates RPS6KB1
ACTB regulates RAB7A
ACTB regulates SREBF1
ACTB regulates EIF4EBP1
ACTB regulates CTSD
ACTB regulates PPARGC1A
ACTB regulates LRP2

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