gene 1,085 words KG: RPS6KB1
Contents

RPS6KB1 Gene

🧬 Gene Info
Gene SymbolRPS6KB1
Chromosome17p13.3
Protein TypeSerine/Threonine Kinase
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight70 kDa
Exons17
PathwaysmTOR, mtor
GeneCardsRPS6KB1
Human Protein AtlasRPS6KB1
Associated DiseasesAD, ADH, AMI, disease, Ischemia, metabolic syndrome
Known Drugs/Compoundsrapamycin
InteractionsActin, AKT, AKT1, AKT1S1, AMBRA1, AMPK
KG Connections547 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (16)

Digital Twin-Guided Metabolic Reprogramming
Score: 0.55
APOE-Dependent Autophagy Restoration
Score: 0.88
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Lysosomal Positioning Dynamics Modulation
Score: 0.69
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67
Nucleolar Stress Response Normalization
Score: 0.65
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (11)

ATP P2X3 Receptor Neurons
cell · KG edge: inhibits
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: inhibits
Apoptosis in Neurodegeneration
entity · KG edge: activates
ACTB Gene
gene · KG edge: regulates
AKT1 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

ACTB regulates RPS6KB1
PPARA regulates RPS6KB1
CAT regulates RPS6KB1
SQSTM1 regulates RPS6KB1
RPS6KB1 regulates RAB7A
RPS6KB1 regulates SREBF1
RPS6KB1 regulates EIF4EBP1
RPS6KB1 regulates CTSD
RPS6KB1 regulates PPARGC1A
RPS6KB1 regulates LRP2

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