concept

TSC22D3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TSC22D3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

57Connections

0Hypotheses

0Analyses

32Outgoing

25Incoming

0Experiments

0Debates

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💡 Concept Info

Name	TSC22D3
Key Genes/Proteins	Actin, ADCY9, ADRA1D, AUTOPHAGY, CALM2, CCND1
Related Pathways	Autophagy, Cell Cycle, Immune Response

Pathway Diagram

graph TD
    TSC22D3["TSC22D3"]
    TSC22D3 -->|"encodes"| GILZ["GILZ"]
    TSC22D3 -->|"regulates"| NPY1R["NPY1R"]
    TSC22D3 -->|"regulates"| Autophagy["Autophagy"]
    TSC22D3 -->|"regulates"| Mtor["Mtor"]
    TSC22D3 -->|"regulates"| Immune_Response["Immune Response"]
    TSC22D3 -->|"regulates"| NFKBIA["NFKBIA"]
    TSC22D3 -->|"regulates"| SESN1["SESN1"]
    TSC22D3 -->|"regulates"| PDK4["PDK4"]
    PPP5C["PPP5C"] -->|"regulates"| TSC22D3
    JUN["JUN"] -->|"regulates"| TSC22D3
    ADRA1D["ADRA1D"] -->|"regulates"| TSC22D3
    PDK4 -->|"regulates"| TSC22D3
    LITAF["LITAF"] -->|"regulates"| TSC22D3
    IL6R["IL6R"] -->|"regulates"| TSC22D3
    CCND1["CCND1"] -->|"regulates"| TSC22D3
    MERTK["MERTK"] -->|"regulates"| TSC22D3

Outgoing (32)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:TSC22D3	data_in	dataset_row	0.00
GILZ	encodes	protein	0.70
ADCY9	regulates	gene	0.60
VPS37B	regulates	gene	0.60
Actin	regulates	protein	0.60
ADRA1D	regulates	gene	0.60
PPP5C	regulates	gene	0.60
LITAF	regulates	gene	0.60
Nfkb	regulates	protein	0.60
DUSP1	regulates	gene	0.60
NPY1R	regulates	gene	0.60
Autophagy	regulates	pathway	0.60
Mtor	regulates	pathway	0.60
Immune Response	regulates	pathway	0.60
NFKBIA	regulates	gene	0.60
SESN1	regulates	gene	0.60
PDK4	regulates	gene	0.60
AUTOPHAGY	regulates	gene	0.60
MYH2	regulates	gene	0.60
CDKN1A	regulates	gene	0.60
JUN	regulates	gene	0.60
NDRG2	regulates	gene	0.60
CALM2	regulates	gene	0.60
MTORC1	regulates	gene	0.60
CCND1	regulates	gene	0.60
GENES	regulates	gene	0.60
SOX2	regulates	gene	0.60
HDC	regulates	gene	0.60
SOX9	regulates	gene	0.60
MERTK	regulates	gene	0.60
IRF1	regulates	gene	0.60
Cell Cycle	regulates	pathway	0.60

Incoming (25)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:TSC22D3	data_in	dataset_row	0.00
HDC	regulates	gene	0.60
PPP5C	regulates	gene	0.60
JUN	regulates	gene	0.60
ADRA1D	regulates	gene	0.60
PDK4	regulates	gene	0.60
LITAF	regulates	gene	0.60
IL6R	regulates	gene	0.60
CCND1	regulates	gene	0.60
MERTK	regulates	gene	0.60
DUSP1	regulates	gene	0.60
ADCY9	regulates	gene	0.60
AUTOPHAGY	regulates	gene	0.60
SOX2	regulates	gene	0.60
CDKN1A	regulates	gene	0.60
SESN1	regulates	gene	0.60
IRF1	regulates	gene	0.60
NDRG2	regulates	gene	0.60
SOX9	regulates	gene	0.60
MYH2	regulates	gene	0.60
VPS37B	regulates	gene	0.60
MTORC1	regulates	gene	0.60
NFKBIA	regulates	gene	0.60
CALM2	regulates	gene	0.60
NPY1R	regulates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning TSC22D3 in their description or question text

No additional research found