gene

adra1d

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about adra1d: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

68Connections

0Hypotheses

0Analyses

44Outgoing

24Incoming

0Experiments

0Debates

No summary available yet.

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	ADRA1D
Full Name	Alpha-1D Adrenergic Receptor
Chromosome	19p13
Primary Expression	the cerebral cortex, hippocampus, thalamus, hypothalamus, and vascular smooth muscle, where it mediates diverse physiological responses
Molecular Weight	60 kDa
Amino Acids	560 aa
Exons	2
Pathways	Autophagy, IMMUNE RESPONSE
UniProt ID	P25100
NCBI Gene ID	146
Ensembl ID	ENSG00000160040
OMIM	104221
GeneCards	ADRA1D
Human Protein Atlas	ADRA1D
Associated Diseases	Alzheimer's disease, Parkinson's disease
KG Connections	12 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: adra1d — AlphaFold P25100 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

ADRA1D Gene

gene · 2002 words

→

Pathway Diagram

graph TD
    ADRA1D["ADRA1D"]
    ADRA1D -->|"regulates"| PDK4["PDK4"]
    ADRA1D -->|"regulates"| LITAF["LITAF"]
    ADRA1D -->|"regulates"| IL6R["IL6R"]
    ADRA1D -->|"regulates"| CCND1["CCND1"]
    ADRA1D -->|"regulates"| MERTK["MERTK"]
    ADRA1D -->|"regulates"| DUSP1["DUSP1"]
    ADRA1D -->|"regulates"| ADCY9["ADCY9"]
    ADRA1D -->|"regulates"| AUTOPHAGY["AUTOPHAGY"]
    PPP5C["PPP5C"] -->|"regulates"| ADRA1D
    JUN["JUN"] -->|"regulates"| ADRA1D
    CCND1 -->|"regulates"| ADRA1D
    LITAF -->|"regulates"| ADRA1D
    IL6R -->|"regulates"| ADRA1D
    HDC["HDC"] -->|"regulates"| ADRA1D
    TSC22D3["TSC22D3"] -->|"regulates"| ADRA1D
    NPY1R["NPY1R"] -->|"regulates"| ADRA1D

Outgoing (44)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:ADRA1D	data_in	dataset_row	0.00
benchmark_ot_ad_answer_key:ADRA1D	data_in	dataset_row	0.00
ds-83b31ef18d49	provides_data_for	dataset	1.00
PDK4	regulates	gene	0.60
LITAF	regulates	gene	0.60
IL6R	regulates	gene	0.60
MERTK	regulates	gene	0.60
DUSP1	regulates	gene	0.60
ADCY9	regulates	gene	0.60
SOX2	regulates	gene	0.60
CDKN1A	regulates	gene	0.60
SESN1	regulates	gene	0.60
IRF1	regulates	gene	0.60
NDRG2	regulates	gene	0.60
SOX9	regulates	gene	0.60
MYH2	regulates	gene	0.60
VPS37B	regulates	gene	0.60
NFKBIA	regulates	gene	0.60
CALM2	regulates	gene	0.60
NPY1R	regulates	gene	0.60
PPP5C	regulates	gene	0.60
JUN	regulates	gene	0.60
CCND1	regulates	gene	0.60
AUTOPHAGY	regulates	gene	0.60
MTORC1	regulates	gene	0.60
TSC22D3	regulates	gene	0.60
Autophagy	regulates	pathway	0.60
Mtor	regulates	pathway	0.60
Immune Response	regulates	pathway	0.60
AND	regulates	gene	0.60
GENES	regulates	gene	0.60
HDC	regulates	gene	0.60
Cell Cycle	regulates	pathway	0.60
Actin	regulates	protein	0.60
Nfkb	regulates	protein	0.60
PDK4	regulates	gene	0.50
MERTK	regulates	gene	0.50
MYH2	regulates	gene	0.50
NPY1R	regulates	gene	0.50
CALM2	regulates	gene	0.50
VPS37B	regulates	gene	0.50
IMMUNE RESPONSE	regulates	pathway	0.50
Autophagy	regulates	process	0.50
IL6R	regulates	gene	0.50

Incoming (24)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:ADRA1D	data_in	dataset_row	0.00
benchmark_ot_ad_answer_key:ADRA1D	data_in	dataset_row	0.00
ds-83b31ef18d49	data_in	dataset	1.00
PPP5C	regulates	gene	0.60
JUN	regulates	gene	0.60
CCND1	regulates	gene	0.60
HDC	regulates	gene	0.60
TSC22D3	regulates	gene	0.60
AUTOPHAGY	regulates	gene	0.60
LITAF	regulates	gene	0.60
IL6R	regulates	gene	0.60
NPY1R	regulates	gene	0.60
MERTK	regulates	gene	0.60
CALM2	regulates	gene	0.60
VPS37B	regulates	gene	0.60
PDK4	regulates	gene	0.60
DUSP1	regulates	gene	0.60
NFKBIA	regulates	gene	0.60
SOX9	regulates	gene	0.60
CDKN1A	regulates	gene	0.60
SESN1	regulates	gene	0.60
MYH2	regulates	gene	0.60
MTORC1	regulates	gene	0.60
adcy9	regulates	gene	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning adra1d in their description or question text

No additional research found