gene

DYNLL1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DYNLL1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

33Connections
0Hypotheses
0Analyses
25Outgoing
8Incoming
0Experiments
0Debates

Summary

DYNLL1 Gene

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🧬 Gene Info
Gene SymbolDYNLL1
Full NameDynein Cytoplasmic 1 Light Chain 1
Chromosome12q12
FunctionDYNLL1 is a component of the dynein motor complex, essential for retrograde axonal transport.
UniProt ID[P63167](https://www.uniprot.org/uniprotkb/P63167/entry)
GeneCardsDYNLL1
Human Protein AtlasDYNLL1
Associated DiseasesAlzheimer's disease, Charcot-Marie-Tooth disease
Known Drugs/Compoundsrapamycin
InteractionsAMPK, ATG5, ATM, ATR, CASP3, CTSB
KG Connections33 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

DYNLL1 Gene

gene · 642 words

Pathway Diagram

flowchart TD
    N0["DYNLL1"]
    N1["EIF4EBP1"]
    N0 -->|"activates"| N1
    N2["GAPDH"]
    N0 -->|"activates"| N2
    N3["GFP"]
    N0 -->|"activates"| N3
    N4["GLUT4"]
    N0 -->|"activates"| N4
    N5["HOMER1"]
    N0 -->|"activates"| N5
    N6["JNK1"]
    N0 -->|"activates"| N6
    N7["LAMP1"]
    N0 -->|"activates"| N7
    N8["LC3"]
    N0 -->|"activates"| N8

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    class N0 gene
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Outgoing (25)

TargetRelationTypeStr
EIF4EBP1activatesgene0.60
GAPDHactivatesgene0.60
HOMER1activatesgene0.60
JNK1activatesgene0.60
LAMP1activatesgene0.60

Incoming (8)

SourceRelationTypeStr
ATG5activatesgene0.60
ATMactivatesgene0.60
ATRactivatesgene0.60
CASP3activatesgene0.60
CTSBactivatesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning DYNLL1 in their description or question text

No additional research found