| Gene Symbol | MITF |
| Full Name | Microphthalmia-Associated Transcription Factor |
| Chromosome | 3p13 |
| Protein Family | bHLH-Zip (MITF/TFEB/TFE3/TFEC) |
| Function | Lysosomal biogenesis, phagocytosis, melanogenesis |
| Primary Expression | Melanocytes, microglia, retinal pigment epithelium |
| Amino Acids | 150 aa |
| Pathways | Dna Repair, Mapk, Pi3K/Akt |
| UniProt ID | O75030 |
| NCBI Gene ID | 4283 |
| Ensembl ID | ENSG00000186766 |
| OMIM | 156845 |
| GeneCards | MITF |
| Human Protein Atlas | MITF |
| LAMP1, LAMP2 | Lysosomal membrane proteins |
| Associated Diseases | Als, Cancer, Melanoma, neurodegeneration, Ovarian Cancer |
| Interactions | Actin, AND, ATG16L1, ATG8, AUTOPHAGY, CGAS |
| SciDEX Hypotheses | MITF Acts as the Primary Transcriptional Effector |
| KG Connections | 238 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!