gene 565 words KG: NEUROD1
Contents

NEUROD1 Gene

🧬 Gene Info
Gene SymbolNEUROD1
Protein TypeGene
FunctionNEUROD1 is a basic helix-loop-helix (bHLH) transcription factor critical for neuronal development and differentiation
Amino Acids396 aa
PathwaysEpigenetic
GeneCardsNEUROD1
Human Protein AtlasNEUROD1
Neuronal differentiationActivates genes required for neuronal maturation
Pancreatic β-cell developmentEssential for insulin-producing β-cell formation
Synaptic plasticityRegulates genes involved in synaptic function
Circadian rhythmPart of the transcriptional feedback loop controlling circadian clocks
Associated DiseasesCancer, Lung Cancer, Tumor
InteractionsASCL1, GENES, KDM6A, NOTCH1, STING
KG Connections128 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (9)

Circadian Clock-Autophagy Synchronization
Score: 0.76
Circadian-Synchronized Proteostasis Enhancement
Score: 0.74
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.72
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Hypocretin-Neurogenesis Coupling Therapy
Score: 0.69
KDM6A-Mediated H3K27me3 Rejuvenation
Score: 0.65
Programmable Neuronal Circuit Repair via Epigenetic CRISPR
Score: 0.63
Temporal Decoupling via Circadian Clock Reset
Score: 0.54

Related Analyses (6)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (14)

Astrocytes
entity · KG edge: expressed_in
ABCB1 (MDR1) - ATP Binding Cassette Subfamily B Member
gene · KG edge: therapeutic_target
ALDH1A1 Gene
gene · KG edge: therapeutic_target
APC Gene
gene · KG edge: therapeutic_target
ASCL1 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

BRG1 therapeutic_target NEUROD1
NRCAM therapeutic_target NEUROD1
NOTCH2 therapeutic_target NEUROD1
EP300 therapeutic_target NEUROD1
CTNNB1 therapeutic_target NEUROD1
NEUROD1 therapeutic_target MYC
NEUROD1 therapeutic_target ABCB1
NEUROD1 therapeutic_target FOXM1
NEUROD1 therapeutic_target LEF1
NEUROD1 therapeutic_target SMARCA4

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