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gene 1,234 words KG: FOXM1
Contents

FOXM1 Gene

🧬 Gene Info
Gene SymbolFOXM1
Chromosome12p13.33
Protein TypeTranscription Factor
FunctionFOXM1 is a key transcriptional regulator of cell cycle and DNA repair genes[@koo2012]:
Molecular Weight82 kDa
Amino Acids664 aa
PathwaysChemoresistance, Complement, Epigenetic, Hedgehog, Nf-Κb
GeneCardsFOXM1
Human Protein AtlasFOXM1
Associated DiseasesCancer, Carcinoma, Lung Cancer, Melanoma, Tumor
InteractionsAKT, AND, APOPTOSIS, AUTOPHAGY, CANCER, FOXO3
KG Connections178 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (11)

Metabolic Switch Targeting for A1→A2 Repolarization
Score: 0.73Metabolic Reprogramming via Microglial Glycolysis Inhibition
Score: 0.67CYP46A1 Overexpression Gene Therapy
Score: 0.92Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.91Transcriptional Autophagy-Lysosome Coupling
Score: 0.88

Related Analyses (4)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archivedNeuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archivedLipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completedCircuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

Apoptosis in Neurodegeneration
entity · KG edge: activatesABCB1 (MDR1) - ATP Binding Cassette Subfamily B Member
gene · KG edge: therapeutic_targetALDH1A1 Gene
gene · KG edge: therapeutic_targetAPC Gene
gene · KG edge: regulatesATF3 Gene
gene · KG edge: therapeutic_target

Knowledge Graph (12 edges)

FGF20 therapeutic_target FOXM1
BRG1 regulates FOXM1
NRCAM therapeutic_target FOXM1
NOTCH2 therapeutic_target FOXM1
EP300 regulates FOXM1
CTNNB1 regulates FOXM1
NEUROD1 therapeutic_target FOXM1
MYC therapeutic_target FOXM1
VEGFA therapeutic_target FOXM1
ABCB1 therapeutic_target FOXM1

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