gene 936 words KG: AXIN1
Contents

AXIN1 Gene

🧬 Gene Info
Gene SymbolAXIN1
Chromosome16p13.3
Protein TypeGene
Functionis a critical scaffolding protein that plays a central role in regulating the Wnt/beta-catenin signaling pathway.
Molecular Weight86 kDa
Amino Acids862 aa
PathwaysWnt, Wnt signaling, Wnt pathway, Wnt Pathway
UniProt IDO15169
NCBI Gene ID351
Ensembl IDENSG00000102837
GeneCardsAXIN1
Human Protein AtlasAXIN1
Associated Diseasesneurodegeneration
InteractionsAKT, ALS, AMPK, AND, ATM, CANCER
KG Connections183 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Phase-Separated Organelle Targeting
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
RNA Granule Nucleation Site Modulation
Score: 0.66

Related Analyses (4)

Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (11)

AMPK (AMP-Activated Protein Kinase)
entity · KG edge: inhibits
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: regulates
ABCB1 (MDR1) - ATP Binding Cassette Subfamily B Member
gene · KG edge: therapeutic_target
ALDH1A1 Gene
gene · KG edge: therapeutic_target
APC Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

FGF20 therapeutic_target AXIN1
BRG1 regulates AXIN1
NRCAM therapeutic_target AXIN1
NOTCH2 therapeutic_target AXIN1
EP300 regulates AXIN1
CTNNB1 regulates AXIN1
NEUROD1 therapeutic_target AXIN1
MYC therapeutic_target AXIN1
VEGFA therapeutic_target AXIN1
ABCB1 therapeutic_target AXIN1

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