| Gene Symbol | MDM2 |
| Full Name | MDM2 Proto-Oncogene, E3 Ubiquitin Protein Ligase |
| Chromosome | 12q15 |
| Protein Type | Ligase |
| Function | MDM2 is a RING-finger E3 ubiquitin ligase with multiple functions: |
| Primary Expression | neurons and glia - Higher expression in cortex and hippocampus - Regulated by neuronal activity |
| Molecular Weight | 55 kDa |
| Amino Acids | 491 aa |
| Pathways | NF-κB |
| UniProt ID | Q00978 |
| NCBI Gene ID | 4193 |
| Ensembl ID | ENSG00000135679 |
| OMIM | 164785 |
| GeneCards | MDM2 |
| Human Protein Atlas | MDM2 |
| Associated Diseases | aging, Als, Alzheimer |
| Known Drugs/Compounds | Pmiγ, PMIγ |
| Interactions | AGING, AKT, AMBRA1, AMPK, AND, APOPTOSIS |
| KG Connections | 524 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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