| Gene Symbol | PTGS2 |
| Full Name | Prostaglandin-Endoperoxide Synthase 2 |
| Aliases | COX-2 |
| Chromosome | 1q31.1 |
| Protein Family | prostaglandin synthase family |
| Protein Type | Enzyme |
| Function | encodes a key enzyme in the prostaglandin biosynthesis pathway that plays a pivotal role in neuroinflammation and neurodegenerative disease pathogenesis. |
| Primary Expression | Constitutive |
| Molecular Weight | 71 kDa |
| Exons | 10 |
| Pathways | NF-κB pathway, NF-κB, MAPK signaling, MAPK |
| UniProt ID | P35354 |
| NCBI Gene ID | 5743 |
| Ensembl ID | ENSG00000073756 |
| OMIM | 600262 |
| GeneCards | PTGS2 |
| Human Protein Atlas | PTGS2 |
| Associated Diseases | Aging, Als, Alzheimer, Cancer, Carcinoma |
| Interactions | ACSL4, ACTB, AKT, AKT1, AND, APOE |
| KG Connections | 659 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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