gene 1,270 words KG: MAP2K1
Contents

MAP2K1 Gene

🧬 Gene Info
Gene SymbolMAP2K1
Full NameMitogen-Activated Protein Kinase Kinase 1
Chromosome15q22.31
Protein FamilyMAP2K family (MAP kinases)
Molecular Weight43 kDa
Amino Acids393 aa
PathwaysMAPK
UniProt IDQ02750
NCBI Gene ID5604
Ensembl IDENSG00000169032
OMIM176872
GeneCardsMAP2K1
Human Protein AtlasMAP2K1
Associated DiseasesTumor
Known Drugs/Compoundstrametinib
InteractionsAND, BRAF, ERK, GENES, KRAS, MAPK1
KG Connections64 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.79
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (14)

Apoptosis in Neurodegeneration
entity · KG edge: associated_with
Genes
index · KG edge: activates
BCL2L1 Gene
gene · KG edge: associated_with
BRAF — B-Raf Proto-Oncogene, Serine/Threonine Kinase
gene · KG edge: activates
CDC42 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

MAP2K1 participates_in sphingolipid signaling pathway
ENO1 biomarker_for MAP2K1
MAP2K1 biomarker_for VCAM1
MAP2K1 biomarker_for LMNA
MAP2K1 biomarker_for GAPDH
BCL2L1 associated_with MAP2K1
MAP2K1 associated_with ANGPT1
MAP2K1 associated_with RHOA
MAP2K1 associated_with EGFR
MAP2K1 associated_with RAF1

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