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index 475 words KG: GENES
Contents

Genes

🔬 Protein Info
Gene SymbolGENES
PathwaysAdaptive Immunity, Akt, Ampk Signaling, Amyloid, Angiogenesis
GeneCardsGENES
Human Protein AtlasGENES
Associated DiseasesAging, Als, Alzheimer, Alzheimer's disease, Amyotrophic Lateral Sclerosis
Interactions6-OHDA, A2M, ABCA1, ABCA7, ABCB1, ABCG1
KG Connections7700 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

Wikipedia

Related Hypotheses (190)

Context-Dependent CRISPR Activation in Specific Neuronal Sub
Score: 0.68Epigenetic Memory Reprogramming for Alzheimer's Disease
Score: 0.61Metabolic Reprogramming via Coordinated Multi-Gene CRISPR Ci
Score: 0.60Circadian-Synchronized LRP1 Pathway Activation
Score: 0.71Chaperone-Mediated APOE4 Refolding Enhancement
Score: 0.68Vagal Afferent Microbial Signal Modulation
Score: 0.62Vocal Cord Neuroplasticity Stimulation
Score: 0.52APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74Proteostasis Enhancement via APOE Chaperone Targeting
Score: 0.72Mechanosensitive Ion Channel Reprogramming
Score: 0.70...
Score: 0.68APOE-Mediated Synaptic Lipid Raft Stabilization
Score: 0.65Transglutaminase-2 Cross-Linking Inhibition Strategy
Score: 0.64Sphingolipid Metabolism Reprogramming
Score: 0.62TREM2-Mediated Selective Aggregate Clearance Pathway
Score: 0.58Tau-Independent Microtubule Stabilization via MAP6 Enhanceme
Score: 0.57HSP70 Co-chaperone DNAJB6 Universal Cross-Seeding Inhibitor
Score: 0.54Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53Axonal RNA Transport Reconstitution
Score: 0.70Cross-Seeding Prevention Strategy
Score: 0.69
pg 1/10Next →

Related Analyses (27)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completedSEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completedCircuit-level neural dynamics in neurodegeneration
neuroscience · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · completedWhich cell types show the most significant expression change
neurodegeneration · completed

Related Experiments (28)

TREM2 Agonist Therapy for Parkinson's Disease — Experimental
validation · proposed · Score: 0.45TREM2 Function in Alzheimer's Disease — From Risk Variant to
validation · proposed · Score: 0.45Microglial TREM2 Agonist In Vivo Efficacy
validation · proposed · Score: 0.45Axonal Transport Dysfunction Validation in Parkinson's Disea
clinical · proposed · Score: 0.40s:** - Single-cell RNA-seq to measure editing efficiency acr
falsification · proposed · Score: 0.40

See Also (15)

OSK Reprogramming and Yamanaka Factors in Neurodegenera
mechanism · Pages share 6 hypothesesABCA2 Gene - ATP Binding Cassette Subfamily A Member 2
gene · KG edge: transportsABCA1 - ATP-Binding Cassette Transporter A1
gene · KG edge: interacts_withABCG1 Gene
gene · KG edge: associated_withABCG2 (BCRP) - ATP Binding Cassette Subfamily G Member
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

GENES associated_with Ms
GENES associated_with DNA
GENES associated_with Autophagy
GENES associated_with Schizophrenia
GENES associated_with ALOX15
GENES associated_with Cardiovascular
HNRNPA2B1 associated_with GENES
HNRNPA1 associated_with GENES
GENES associated_with VCP
GENES associated_with TIA1

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