gene 1,654 words KG: VCAM1
Contents

VCAM1 - Vascular Cell Adhesion Molecule 1

🧬 Gene Info
Gene SymbolVCAM1
Full NameVascular Cell Adhesion Molecule 1
AliasesCD106
Chromosome1p21.2
FunctionCell adhesion molecule mediating leukocyte endothelial attachment
Molecular Weight81.3 kDa
Amino Acids739
PathwaysLeukocyte extravasation, NF-kB signaling
UniProt IDP19320
NCBI Gene ID7412
Ensembl IDENSG00000162692
GeneCardsVCAM1
Human Protein AtlasVCAM1
Associated DiseasesAls, Alzheimer, dementia, Inflammation, Multiple Sclerosis
InteractionsAkt, AKT, AMPK, AND, APOPTOSIS, BAX
KG Connections177 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (6)

Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72

Related Analyses (3)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Astrocytes
cell · KG edge: protects_against
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
BACE1 (Redirect)
redirect · KG edge: protects_against
BAX Gene
gene · KG edge: inhibits
CD44 - Cell Surface Glycoprotein
gene · KG edge: associated_with

Knowledge Graph (12 edges)

CXCL10 associated_with VCAM1
TNF associated_with VCAM1
BAX inhibits VCAM1
CXCL2 associated_with VCAM1
PTGS2 associated_with VCAM1
MMP9 associated_with VCAM1
VCAM1 associated_with ICAM1
ICAM1 inhibits VCAM1
VCAM1 inhibits LDLR
VCAM1 inhibits TNF

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)