gene 789 words KG: CACNA1E
Contents

CACNA1E Gene

🧬 Gene Info
Gene SymbolCACNA1E
Full NameCalcium Voltage-Gated Channel Subunit Alpha1 E
AliasesCav2.3 R-type Calcium Channel
Chromosome1q25.1
FunctionThe CACNA1E gene encodes the α1E subunit that forms the pore of the R-type voltage-gated calcium channel (CaV2.3).
Primary Expressionhippocampal neurons, cerebellar granule cells, and various cortical regions - Dendritic localization: Primarily located on de
Molecular Weight250 kDa
Amino Acids233 aa
UniProt IDQ15878
NCBI Gene ID777
Ensembl IDENSG00000198004
GeneCardsCACNA1E
Human Protein AtlasCACNA1E
Associated DiseasesAls
InteractionsCACNA1A, CACNA1C, CACNA1D, cacna1f, CACNA1F, CACNA1G
KG Connections70 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (2)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

blarcamesine-axon
clinical_trial · KG edge: regulates
BIN1 — Bridging Integrator 1
gene · KG edge: associated_with
CACNA1A — Calcium Channel Alpha-1A Subunit
gene · KG edge: associated_with
CACNA1C Gene
gene · KG edge: associated_with
CACNA1D Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

EPAS1 associated_with CACNA1E
CACNG6 associated_with CACNA1E
BIN1 associated_with CACNA1E
CHRNA2 therapeutic_target CACNA1E
CEBPA associated_with CACNA1E
CNR1 therapeutic_target CACNA1E
CTSD associated_with CACNA1E
NME1 therapeutic_target CACNA1E
CACNA1E associated_with CACNA2D3
CACNA1E therapeutic_target PRKAB1

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)