| Gene Symbol | NME1 |
| Full Name | NME/Nucleoside Diphosphate Kinase 1 |
| Aliases | Page for NME1 Protein |
| Chromosome | 17q21.33 |
| Protein Type | Enzyme |
| Function | is a ubiquitous enzyme that catalyzes the transfer of phosphate groups between nucleoside diphosphates (NDPs) and nucleoside triphosphates (NTPs). |
| Primary Expression | most human tissues: |
| Molecular Weight | 17 kDa |
| Amino Acids | 152 aa |
| UniProt ID | [P15531](https://www.uniprot.org/uniprot/P15531) |
| Ensembl ID | ENSG00000214021 |
| GeneCards | NME1 |
| Human Protein Atlas | NME1 |
| N-terminal domain | Contains the phosphate-binding loop (P-loop) motif essential for nucleotide binding |
| Active site | His-118 serves as the central histidine residue mediating phosphate transfer |
| Associated Diseases | Als, Leukemia, Ms |
| Interactions | ASH1L, CAV1, RELN |
| KG Connections | 41 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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