gene 1,037 words KG: CACNA2D1
Contents

CACNA2D1 Gene - Calcium Channel Voltage-Dependent Subunit Alpha2 Delta 1

🧬 Gene Info
Gene SymbolCACNA2D1
Full NameCalcium Channel Voltage-Dependent Subunit Alpha2 Delta 1
Chromosome7q21.11
Protein TypeChannel
Functionis a critical component of L-type and N-type calcium channels, modulating channel trafficking, gating, and synaptic localization.
Primary ExpressionHigh in brain, skeletal muscle, heart
Amino Acids1256 aa
UniProt IDQ13926
NCBI Gene ID781
Ensembl IDENSG00000153991
OMIM114204
GeneCardsCACNA2D1
Human Protein AtlasCACNA2D1
Associated Diseasesneurodegeneration
InteractionsCACNA1A, CACNA1C, CACNA1D, CACNA1E, cacna1f, CACNA1F
KG Connections39 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (11)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
CYP46A1 Overexpression Gene Therapy
Score: 0.92
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lysosomal Calcium Channel Modulation Therapy
Score: 0.70

Related Analyses (10)

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed

See Also (12)

Neurodegeneration
disease · KG edge: implicated_in
CACNA1A — Calcium Channel Alpha-1A Subunit
gene · KG edge: associated_with
CACNA1C Gene
gene · KG edge: associated_with
CACNA1D Gene
gene · KG edge: associated_with
CACNA1E Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

CACNA1A associated_with CACNA2D1
CCS contributes_to CACNA2D1
CACNA1C associated_with CACNA2D1
CACNA2D2 associated_with CACNA2D1
CACNA1F associated_with CACNA2D1
CACNA1I associated_with CACNA2D1
CACNA2D1 associated_with CACNA1E
CACNA2D1 associated_with CACNA1H
CACNA2D1 associated_with CACNA1D
CACNA2D1 associated_with CACNA1G

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