| Gene Symbol | CACNA2D3 |
| Protein Type | Gene |
| Function | CACNA2D3 resides on chromosome 3p21.1 and produces a precursor polypeptide that is post-translationally cleaved into alpha2 and delta components, which remain linked by disulfide bonds. |
| GeneCards | CACNA2D3 |
| Human Protein Atlas | CACNA2D3 |
| Trafficking amplifier | boosts membrane delivery and stability of Cav channel complexes.[@dolphin2012][@eroglu2009] |
| Kinetic modulation | alters channel activation/inactivation profile and calcium current density.[@dolphin2012] |
| Synaptogenic signaling interface | alpha2delta proteins can engage extracellular matrix ligands that shape synapse formation and maturation.[@eroglu2009] |
| Associated Diseases | neurodegeneration |
| KG Connections | 13 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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