gene 1,769 words KG: CEBPA
Contents

CEBPA Gene

🧬 Gene Info
Gene SymbolCEBPA
AliasesCCAAT/Enhancer Binding Protein Alpha
Protein TypeGene
Functionencodes a transcription factor belonging to the C/EBP family of basic leucine zipper (bZIP) proteins.
Primary ExpressionBroad tissue distribution; high expression in liver, adipose tissue, and hematopoietic cells; moderate expression in brain (astrocytes, microglia, neu
Molecular Weight42 kDa
PathwaysApoptosis, Cholesterol
UniProt IDP49715
NCBI Gene ID1050
Ensembl IDENSG00000172270
OMIM116897
GeneCardsCEBPA
Human Protein AtlasCEBPA
Full nameCCAAT/Enhancer Binding Protein Alpha
Chromosomal locus19q13.11
Associated DiseasesALS, Alzheimer, Multiple Sclerosis, Parkinson
KG Connections134 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (6)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Lysosomal Positioning Dynamics Modulation
Score: 0.69
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.67
DNMT1-Targeting Antisense Oligonucleotide Reset
Score: 0.65
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62

Related Analyses (6)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived

See Also (11)

Apoptosis in Neurodegeneration
entity · KG edge: regulates
ATF3 Gene
gene · KG edge: protects_against
BANG — BAG3 (Bcl-2-Associated Athanogene 3)
gene · KG edge: regulates
BIN1 — Bridging Integrator 1
gene · KG edge: associated_with
CACNA1E Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

CEBPA therapeutic_target HSPA1A
CEBPA regulates TFE3
CEBPA regulates TP53
CEBPA regulates SPI1
HSPA1A therapeutic_target CEBPA
SPI1 regulates CEBPA
EPAS1 associated_with CEBPA
CACNG6 associated_with CEBPA
BIN1 associated_with CEBPA
CHRNA2 therapeutic_target CEBPA

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