Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NK CELL: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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graph TD
NK_CELL["NK CELL"]
NK_CELL -->|"inhibits"| TUMOR["TUMOR"]
NK_CELL -->|"activates"| T_CELL["T CELL"]
NK_CELL -->|"activates"| T_CELLS["T CELLS"]
STAT3["STAT3"] -->|"activates"| NK_CELL
CYTOKINES["CYTOKINES"] -->|"contributes to"| NK_CELL
TAU["TAU"] -->|"contributes to"| NK_CELL
OVERVIEW["OVERVIEW"] -->|"contributes to"| NK_CELL
ALZHEIMER["ALZHEIMER"] -->|"contributes to"| NK_CELL
CD38["CD38"] -->|"expressed in"| NK_CELL
HLA["HLA"] -->|"causes"| NK_CELL| Source | Relation | Type | Str |
|---|---|---|---|
| CD38 | expressed_in | gene | 0.60 |
| CD38 | regulates | gene | 0.60 |
| KDM6A | regulates | gene | 0.60 |
| EZH2 | regulates | gene | 0.60 |
| ALZHEIMER | contributes_to | gene | 0.60 |
| PD-L1 | therapeutic_target | gene | 0.60 |
| HLA | causes | gene | 0.60 |
| HGF | therapeutic_target | gene | 0.60 |
| MICROGLIA | associated_with | gene | 0.60 |
| UBIQUITIN | expressed_in | gene | 0.60 |
| CYTOKINES | contributes_to | gene | 0.60 |
| ARG1 | therapeutic_target | gene | 0.60 |
| RAD18 | activates | gene | 0.60 |
| E2F7 | activates | gene | 0.60 |
| STROKE | associated_with | gene | 0.60 |
| STAT3 | activates | gene | 0.60 |
| TAU | contributes_to | gene | 0.60 |
| OVERVIEW | contributes_to | gene | 0.60 |
| GLS | therapeutic_target | gene | 0.60 |
| Ischemia | activates | disease | 0.55 |
| Stroke | associated_with | disease | 0.55 |
| Als | activates | disease | 0.55 |
| Als | regulates | disease | 0.55 |
| Cancer | activates | disease | 0.55 |
| Neurodegeneration | contributes_to | disease | 0.55 |
| Neuroinflammation | contributes_to | disease | 0.55 |
| Alzheimer | contributes_to | disease | 0.55 |
| Als | causes | disease | 0.55 |
| Cancer | therapeutic_target | disease | 0.55 |
| Cancer | expressed_in | disease | 0.55 |
| Als | therapeutic_target | disease | 0.55 |
| Aging | therapeutic_target | disease | 0.55 |
| CANCER | expressed_in | gene | 0.55 |
| IMMUNE INFILTRATION | expressed_in | gene | 0.55 |
| INFLAMMATION | expressed_in | gene | 0.55 |
| CYTOKINES | expressed_in | gene | 0.55 |
| BRAIN INJURY | expressed_in | gene | 0.55 |
| IFN | expressed_in | gene | 0.55 |
| STROKE | expressed_in | gene | 0.55 |
| JAK | expressed_in | gene | 0.55 |
| IFN-Γ | expressed_in | gene | 0.55 |
| STAT3 | expressed_in | gene | 0.55 |
| AND | expressed_in | gene | 0.55 |
| Immune Response | activates | pathway | 0.50 |
| Blood-Brain Barrier | contributes_to | pathway | 0.50 |
| Innate Immunity | expressed_in | pathway | 0.50 |
| ISCHEMIC | co_discussed | disease | 0.40 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning NK CELL in their description or question text
No additional research found