concept

GHRELIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GHRELIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

45Connections

0Hypotheses

0Analyses

12Outgoing

33Incoming

0Experiments

0Debates

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💡 Concept Info

Name	GHRELIN

Pathway Diagram

graph TD
    GHRELIN["GHRELIN"]
    GHRELIN -.biomarker for.-> Aging["Aging"]
    GHRELIN -.biomarker for.-> Fibrosis["Fibrosis"]
    GHRELIN -.biomarker for.-> Senescence["Senescence"]
    GHRELIN -->|"activates"| Als["Als"]
    GHRELIN -.protects against.-> Parkinson["Parkinson"]
    GHRELIN -->|"activates"| Obesity["Obesity"]
    GHRELIN -.biomarker for.-> Apoptosis["Apoptosis"]
    GHRELIN -->|"expressed in"| Autophagy["Autophagy"]
    VIM["VIM"] -.biomarker for.-> GHRELIN
    MITOCHONDRIA["MITOCHONDRIA"] -.biomarker for.-> GHRELIN
    PROGRANULIN["PROGRANULIN"] -.biomarker for.-> GHRELIN
    VIMENTIN["VIMENTIN"] -.biomarker for.-> GHRELIN
    TGM2["TGM2"] -->|"activates"| GHRELIN
    PGRN["PGRN"] -.biomarker for.-> GHRELIN
    FGF21["FGF21"] -.biomarker for.-> GHRELIN
    CX3CL1["CX3CL1"] -.biomarker for.-> GHRELIN

Outgoing (12)

Target	Relation	Type	Str
Obesity	activates	disease	0.60
Senescence	biomarker_for	disease	0.60
Aging	biomarker_for	disease	0.60
Als	activates	disease	0.60
Fibrosis	biomarker_for	disease	0.60
Als	associated_with	disease	0.60
Parkinson	protects_against	disease	0.60
Ptsd	associated_with	disease	0.60
Autophagy	expressed_in	pathway	0.55
Synaptic Plasticity	activates	pathway	0.55
Apoptosis	biomarker_for	pathway	0.55
Phagocytosis	activates	pathway	0.55

Incoming (33)

Source	Relation	Type	Str
MITOCHONDRIA	biomarker_for	gene	0.60
PGRN	biomarker_for	gene	0.60
AMYLOID	activates	gene	0.60
IL-6	biomarker_for	gene	0.60
GHRL	activates	gene	0.60
APOPTOSIS	biomarker_for	gene	0.60
IGF-1	activates	gene	0.60
GHRL	associated_with	gene	0.60
MICROGLIA	activates	gene	0.60
PHAGOCYTOSIS	activates	gene	0.60
VIM	biomarker_for	gene	0.60
PROGRANULIN	biomarker_for	gene	0.60
AGING	biomarker_for	gene	0.60
COMPLEMENT	activates	gene	0.60
VIMENTIN	biomarker_for	gene	0.60
TGM2	activates	gene	0.60
FGF21	biomarker_for	gene	0.60
CX3CL1	biomarker_for	gene	0.60
HMGB1	activates	gene	0.60
PLAU	biomarker_for	gene	0.60
S100B	activates	gene	0.60
GPNMB	activates	gene	0.60
APP	activates	gene	0.60
BDNF	biomarker_for	gene	0.60
FGF23	biomarker_for	gene	0.60
CXCL10	biomarker_for	gene	0.60
FNDC5	biomarker_for	gene	0.60
PARKINSON	protects_against	gene	0.60
AUTOPHAGY	expressed_in	gene	0.60
HCRTR1	associated_with	gene	0.60
HCRTR2	associated_with	gene	0.60
C1Q	activates	gene	0.60
CD68	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning GHRELIN in their description or question text

No additional research found