gene

EEF1A1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about EEF1A1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

92Connections

0Hypotheses

0Analyses

50Outgoing

22Incoming

0Experiments

0Debates

No summary available yet.

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	EEF1A1
Full Name	Eukaryotic Translation Elongation Factor 1 Alpha 1
Aliases	EF-1-alpha-1, EF1A
Chromosome	6q14.1
Protein Type	Gene
Function	Delivers aminoacyl-tRNA to ribosome during translation
Subcellular Localization	contribute to the molecular cascades underlying neuronal death in both Alzheimer's and Parkinson's disease contexts.[@s2
Molecular Weight	50.1 kDa
Amino Acids	462
Pathways	Translation elongation, Protein synthesis
UniProt ID	P68104
Ensembl ID	ENSG00000156508
GeneCards	EEF1A1
Human Protein Atlas	EEF1A1
Associated Diseases	AD, ALI, Als, AMI, cancer
Interactions	APOB, CANCER, IDH1, JUN, MCL1, MDM4
KG Connections	92 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: EEF1A1 — AlphaFold P68104 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

eef1a1

gene · 2617 words

→

Pathway Diagram

graph TD
    EEF1A1["EEF1A1"] -->|"therapeutic target"| Cancer["Cancer"]
    style Cancer fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#e0e0e0
    EEF1A1["EEF1A1"] -->|"therapeutic target"| Carcinoma["Carcinoma"]
    style Carcinoma fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#e0e0e0
    EEF1A1["EEF1A1"] -->|"therapeutic target"| Ms["Ms"]
    style Ms fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#e0e0e0
    EEF1A1["EEF1A1"] -->|"therapeutic target"| Als["Als"]
    style Als fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#e0e0e0
    EEF1A1["EEF1A1"] -->|"therapeutic target"| MCL1["MCL1"]
    style MCL1 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#e0e0e0
    EEF1A1["EEF1A1"] -->|"therapeutic target"| Dna_Methylation["Dna Methylation"]
    style Dna_Methylation fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#e0e0e0
    EEF1A1["EEF1A1"] -->|"therapeutic target"| Wnt["Wnt"]
    style Wnt fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#e0e0e0
    IDH1["IDH1"] -->|"therapeutic target"| EEF1A1["EEF1A1"]
    style IDH1 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#e0e0e0
    VEGFA["VEGFA"] -->|"therapeutic target"| EEF1A1["EEF1A1"]
    style VEGFA fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#e0e0e0
    MDM4["MDM4"] -->|"therapeutic target"| EEF1A1["EEF1A1"]
    style MDM4 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#e0e0e0
    APOB["APOB"] -->|"therapeutic target"| EEF1A1["EEF1A1"]
    style APOB fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#e0e0e0
    SF3B1["SF3B1"] -->|"associated"| EEF1A1["EEF1A1"]
    style SF3B1 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#e0e0e0
    style EEF1A1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold

Outgoing (70)

Target	Relation	Type	Str
Carcinoma	inhibits	disease	0.65
ALS	inhibits	disease	0.65
Carcinoma	associated_with	disease	0.65
Cancer	associated_with	disease	0.65
Als	associated_with	disease	0.65
Cancer	inhibits	disease	0.65
Als	therapeutic_target	disease	0.65
Ms	therapeutic_target	disease	0.65
Cancer	therapeutic_target	disease	0.65
Carcinoma	therapeutic_target	disease	0.65
MET	therapeutic_target	gene	0.60
IDH1	associated_with	gene	0.60
MCL1	associated_with	gene	0.60
MDM4	associated_with	gene	0.60
SF3B1	associated_with	gene	0.60
SMARCA4	associated_with	gene	0.60
TERT	associated_with	gene	0.60
VEGFA	associated_with	gene	0.60
MDM4	inhibits	gene	0.60
JUN	inhibits	gene	0.60
MET	inhibits	gene	0.60
MCL1	inhibits	gene	0.60
VEGFA	inhibits	gene	0.60
APOB	inhibits	gene	0.60
TERT	inhibits	gene	0.60
IDH1	inhibits	gene	0.60
JUN	therapeutic_target	gene	0.60
IDH1	therapeutic_target	gene	0.60
TERT	therapeutic_target	gene	0.60
APOB	therapeutic_target	gene	0.60
Vegf	therapeutic_target	protein	0.60
Rb	therapeutic_target	protein	0.60
Wnt	inhibits	pathway	0.60
AND	associated_with	gene	0.60
PD-1	inhibits	gene	0.60
RNA	therapeutic_target	gene	0.60
PD-1	therapeutic_target	gene	0.60
PD-L1	therapeutic_target	gene	0.60
Erk	therapeutic_target	protein	0.60
MCL1	therapeutic_target	gene	0.60
MDM4	therapeutic_target	gene	0.60
VEGFA	therapeutic_target	gene	0.60
Dna Methylation	therapeutic_target	pathway	0.60
Wnt	therapeutic_target	pathway	0.60
P53	therapeutic_target	gene	0.60
P53	associated_with	gene	0.60
Dna Methylation	associated_with	pathway	0.60
Wnt	associated_with	pathway	0.60
DNA	associated_with	gene	0.60
GENES	associated_with	gene	0.60

Incoming (22)

Source	Relation	Type	Str
APOB	inhibits	gene	0.60
PD-L1	inhibits	gene	0.60
WNT	inhibits	gene	0.60
LZTR1	associated_with	gene	0.60
DNA	associated_with	gene	0.60
GENES	associated_with	gene	0.60
IDH1	therapeutic_target	gene	0.60
VEGFA	therapeutic_target	gene	0.60
MDM4	therapeutic_target	gene	0.60
APOB	therapeutic_target	gene	0.60
SF3B1	associated_with	gene	0.60
MET	therapeutic_target	gene	0.60
SMARCA4	associated_with	gene	0.60
TERT	therapeutic_target	gene	0.60
JUN	therapeutic_target	gene	0.60
APOB	associated_with	gene	0.60
MCL1	therapeutic_target	gene	0.60
WNT	therapeutic_target	gene	0.60
PD-L1	therapeutic_target	gene	0.60
RNA	therapeutic_target	gene	0.60
PD-1	therapeutic_target	gene	0.60
P53	therapeutic_target	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning EEF1A1 in their description or question text

No additional research found