gene 835 words KG: UBC
Contents

UBC

🧬 Gene Info
Gene SymbolUBC
AliasesUbiquitin C
Chromosome12q24.31
Protein TypeEnzyme
Functionis a highly conserved 76-amino acid protein that plays a central role in the ubiquitin-proteasome system (UPS) and lysosomal degradation pathways.
Molecular Weight8.5 kDa
Amino Acids76 aa
PathwaysNF-κB
GeneCardsUBC
Human Protein AtlasUBC
Associated DiseasesAls, Alzheimer, Cancer, Ischemia, Ms
InteractionsAPP, CTNNB1, EGFR, FN1, GRB2, HSP90AA1
KG Connections198 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
VCP-Mediated Autophagy Enhancement
Score: 0.59
HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57
Prohibitin-2 Mitochondrial Cross-Seeding Hub Disruption
Score: 0.47
Piezoelectric Nanochannel BBB Disruption
Score: 0.52

Related Analyses (2)

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Apoptosis in Neurodegeneration
entity · KG edge: expressed_in
ACTB Gene
gene · KG edge: regulates
ATG12 — Autophagy Related 12
gene · KG edge: associated_with
ATG3 Gene
gene · KG edge: associated_with
ATG7 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

DRD2 associated_with UBC
FYN associated_with UBC
SRC associated_with UBC
CAMK2A associated_with UBC
SNCA associated_with UBC
SLC6A3 associated_with UBC
UBC associated_with HOMER1
UBC associated_with COMT
COMT associated_with UBC
HOMER1 associated_with UBC

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.