| Gene Symbol | CSNK2A2 |
| Chromosome | 16p13.3 |
| Function | ### CK2 Holoenzyme Composition |
| Amino Acids | 350 aa |
| Exons | 12 |
| Pathways | Mitophagy, Cgas-Sting, autophagy pathway |
| Ensembl ID | ENSG00000070770 |
| GeneCards | CSNK2A2 |
| Human Protein Atlas | CSNK2A2 |
| High homology | 90% identical to CK2α in the catalytic domain |
| Distinct C-terminus | Different from CK2α, contributing to unique substrate specificity |
| Tissue-specific expression | More restricted pattern than CSNK2A1 |
| α'₂β₂ | Homotetramer with two α' catalytic subunits |
| αα'β₂ | Heterotetramer mixing α and α' subunits |
| Substrate differences | Some substrates preferentially phosphorylated by α' vs α |
| Associated Diseases | Ischemia |
| KG Connections | 37 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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