gene 546 words KG: CYCS
Contents

CYCS

🧬 Gene Info
Gene SymbolCYCS
Full NameCytochrome c
Chromosome7p15.3
FunctionCytochrome c (CYCS) is a small heme protein located in the mitochondrial intermembrane space that plays a central role in both cellular respiration and apoptosis.
Primary Expressionall aerobic cells, with highest levels in tissues with high metabolic rates including brain, heart, liver, and kidney
PathwaysOxidative Phosphorylation
UniProt ID[P99999](https://www.uniprot.org/uniprot/P99999)
Ensembl IDENSG00000172115
OMIM123970
GeneCardsCYCS
Human Protein AtlasCYCS
Associated DiseasesAls, Alzheimer, Dementia, Diabetes, Inflammation, Ms
Known Drugs/Compoundsrapamycin
Interactionsaco2, ACO2, ACTB, APP, ATG5, ATP
KG Connections355 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (8)

Digital Twin-Guided Metabolic Reprogramming
Score: 0.55
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.82
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.79
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57

Related Analyses (3)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (13)

ATP P2X3 Receptor Neurons
cell · KG edge: therapeutic_target
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: inhibits
ACO2 — Aconitase 2
gene · KG edge: expressed_in
ACTB Gene
gene · KG edge: inhibits
ATG12 — Autophagy Related 12
gene · KG edge: associated_with

Knowledge Graph (12 edges)

SOD2 associated_with CYCS
CDC42 associated_with CYCS
CYCS associated_with GFAP
CYCS therapeutic_target RAC1
CYCS therapeutic_target MET
CYCS associated_with MMP9
CYCS associated_with VIM
CYCS therapeutic_target TPM2
CYCS associated_with NCF1
MET therapeutic_target CYCS

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