gene 790 words KG: MFF
Contents

MFF Gene

🧬 Gene Info
Gene SymbolMFF
Full NameMitochondrial Fission Factor
Chromosome5q31.2
Protein TypeReceptor
FunctionMFF is the major mitochondrial outer membrane receptor for DRP1 (Dynamin 1-like protein), mediating mitochondrial fission through
Gene TypeProtein-coding
PathwaysImmune Response, Mitochondrial Function, Mitophagy, Oxidative Stress, Wnt
UniProt IDQ9NXG2
NCBI Gene ID27245
Ensembl IDENSG00000168955
OMIM614785
GeneCardsMFF
Human Protein AtlasMFF
Associated DiseasesAls, Parkinson, Tumor
InteractionsABP, Akt, AKT, AMPK, ATG16L1, BCL2
KG Connections271 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (7)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
CYP46A1 Overexpression Gene Therapy
Score: 0.73
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Autophagosome Maturation Checkpoint Control
Score: 0.71
Mitochondrial Transfer Pathway Enhancement
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67

Related Analyses (5)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
BCL2 Gene
gene · KG edge: associated_with
BCL2L13
gene · KG edge: associated_with
BDNF Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

DRP1 interacts_with MFF
TOMM20 regulates MFF
MAX regulates MFF
MIRO1 interacts_with MFF
MID51 interacts_with MFF
MID49 interacts_with MFF
MFF interacts_with DRP1
MFF regulates MAX
MFF regulates TOMM20
MFF interacts_with MIRO1

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.