gene 2,561 words KG: ANG
Contents

ANG — Angiogenin

🧬 Gene Info
Gene SymbolANG
Full NameAngiogenin
AliasesGene profile: ANG
Chromosome14q11.2
Protein TypeProtein
Functionis a multifunctional protein that plays critical roles in both physiological and pathological processes within the nervous system.
Molecular Weight14 kDa
Amino Acids147 aa
Exons2
PathwaysNF-κB
UniProt IDSearch UniProt
GeneCardsANG
Human Protein AtlasANG
Associated DiseasesCardiac, Heart Failure, Hypertension, Inflammation, Neuroinflammation
InteractionsActin, AGING, AKT, AND, ANXA2, APOE
KG Connections266 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (30)

TREM2-Dependent Microglial Senescence Transition
Score: 0.95
Selective Acid Sphingomyelinase Modulation Therapy
Score: 0.92
CYP46A1 Overexpression Gene Therapy
Score: 0.92
Membrane Cholesterol Gradient Modulators
Score: 0.71
Sphingomyelin Synthase Activators for Raft Remodeling
Score: 0.69

Related Analyses (6)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · archived
SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived

See Also (9)

Astrocytes
cell · KG edge: expressed_in
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: expressed_in
ACE Gene
gene · KG edge: implicated_in
ANXA2 — Annexin A2
gene · KG edge: activates
APOE contributes to Alzheimer's disease by regulating b
hypothesis · KG edge: activates

Knowledge Graph (12 edges)

PKC inhibits ANG
ANG activates KCNK2
ANG inhibits KCNK2
ANG activates NRP1
ANG associated_with APOE
ANG protects_against SLC44A2
TRPA1 regulates ANG
CAT activates ANG
ANG activates PIEZO1
ANG activates PIEZO2

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