gene 828 words KG: ent-gene-59933b8f
Contents

ATG14 Gene

🧬 Gene Info
Gene SymbolATG14
Full NameAutophagy Related 14
Chromosome10q26.3
Functionis a crucial autophagy protein that plays a central role in the initiation of autophagosome formation.
Amino Acids492 aa
Exons12
PathwaysApoptosis, Autophagy, Cell Cycle, Epithelial-Mesenchymal Transition, Inflammasome
UniProt IDQ9Y5P8
NCBI Gene ID22889
Ensembl IDENSG00000131725
OMIM614113
GeneCardsATG14
Human Protein AtlasATG14
Associated DiseasesALS, Cancer, dementia, frontotemporal, Infection, Lung Cancer
InteractionsACTB, AIM2, AMPK, AND, APOPTOSIS, AR
KG Connections324 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (12)

APOE-Dependent Autophagy Restoration
Score: 0.88
Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.79
Transcriptional Autophagy-Lysosome Coupling
Score: 0.76
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astroglial Gap Junction Coordination via Connexin-43 Phospho
Score: 0.72
Autophagosome Maturation Checkpoint Control
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Lysosomal Positioning Dynamics Modulation
Score: 0.69
CX43 hemichannel engineering enables size-selective mitochon
Score: 0.69
Quantum Coherence Disruption in Cellular Communication
Score: 0.63
VCP-Mediated Autophagy Enhancement
Score: 0.59
Astrocytic Connexin-43 Upregulation Enhances Neuroprotective
Score: 0.56

Related Analyses (7)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived

See Also (15)

AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: activates
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: regulates
ACTB Gene
gene · KG edge: associated_with
ar
gene · KG edge: activates

Knowledge Graph (2 edges)

ent-gene-59933b8f data_in benchmark_ot_ad_answer_key:ATG14
benchmark_ot_ad_answer_key:ATG14 data_in ent-gene-59933b8f

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